ID G7NIR6_MACMU Unreviewed; 1792 AA.
AC G7NIR6;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Myosin-13 {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=EGK_08194 {ECO:0000313|EMBL:EHH24529.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH24529.1};
RN [1] {ECO:0000313|EMBL:EHH24529.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR-5 {ECO:0000313|EMBL:EHH24529.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001268; EHH24529.1; -; Genomic_DNA.
DR Proteomes; UP000013456; Chromosome 16.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0032982; C:myosin filament; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 4.
DR Gene3D; 1.20.58.530; -; 2.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 6.10.250.2420; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 2.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 4.10.270.10; Myosin, subunit A; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF44; MYOSIN-13; 1.
DR Pfam; PF00063; Myosin_head; 2.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF57997; Tropomyosin; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 2.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Muscle protein {ECO:0000256|ARBA:ARBA00023179};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Thick filament {ECO:0000256|ARBA:ARBA00022433}.
FT DOMAIN 33..82
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 86..538
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 584..640
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 1769..1792
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 704..1096
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1769..1783
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 179..186
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT NON_TER 1792
FT /evidence="ECO:0000313|EMBL:EHH24529.1"
SQ SEQUENCE 1792 AA; 206907 MW; 75BEF20573AB8F39 CRC64;
MSSDAEMAIF GEAAPYLRKP EKERIEAQNR PFDSKKACFV ADDKEMYVKG MIQSRENDKV
IVKTLDDRTL TLNNDQVFPM NPPKFDKIED MAMMTHLHEP AVLYNLKERY AAWMIYTYSG
LFCVTVNPYK WLPVYNPEVV AAYRGKKRQE APPHIFSISD NAYQFMLTDR DNQSILITGE
SGAGKTVNTK RVIQYFATIA VTGDKKKETQ PGKMQGTLED QIIQANPLLE AFGNAKTVRN
DNSSRFGKFI RIHFGATGKL ASADIETYLL EKSRVTFQLS SERSYHIFYQ ILSNKKPELI
DLLLISTNPF DFPFVSQGEV TVASIDDSEE LLATDNAIDI LGFSSEEKVG IYKLTGAVMH
YGNMKFKQKQ REEQAEPDGT EVADKAGYLM GLNSAEMLKG LCCPRVKVGN EYVTKGQNVQ
QVTNSVGALA KAVYEKMFLW MVTRINQQLD TKQPRQYFIG VLDIAGFEIF DFNSLEQLCI
NFTNEKLQQF FNHHMFVLEQ EEYKKEGIEW EFIDFAMDLA ACIELIEKGD SGGSKKGGKK
KGSSFQTVSA VFRENLNKLM TNLRSTHPHF VRCLIPNETK TPGYRILNAS AIPEGQFIDS
KNASEKLLNS IDVDREQFRF GNTKVFFKAG LLGLLEEMRD EKLVTLMTRT QAVCRGYLMR
VEFKKMMERR DSIFCIQYNI RSFMNVKHWP WMNLFFKIKP LLKSAEAEKE MATMKEDFER
TKEELARSEA RRKELEEKMV SLLQEKNDLQ LQVQSETENL MDAEERCEGL IKSKILLEAK
VKELTERLEE EEDMNSELVA KKRNLEDKCC SLKRDIDDLE LTLTKVEKEK HATENKVKNL
SEEMTALEEN ISKLTKEKKS LQEAHQQTLD DLQVEEDKVN GLIKINAKLE QQTDDLEGSL
EQEKKLRADL ERAKRKLEGD LKMSQESIMD LENDKQQIEE KLKKKEFEIS QLQAKIDDEQ
VHSWQFQKKM KELQARIEEL EEEIEAEHTL RAKIEKQRSD LARELEEISE RLEEASGATS
AQIEMNKKRE AEFQKMRRDL EEATLQHEAT VATLRKKHAD SVAELGEQID NLQRVKQKLE
KEKSELKMEI DDMASNIEAI SKSKSNIERT CRTVEDQFSE IKAKDEQQTQ LIHDLNMQKA
RLQTQNGELS HQVEEKESLI SQLTKSKQAL TQQLEELKRQ MEEETKAKNA LAHALQSSRH
DCDLLREQYE EEQEGKAELQ RALSKANSEV AQWRTKYETD AIQRTEELEE AKKKLAQRLQ
EAEENTETAN SKCASLEKTK QRLQGEVDDL MLDLERSHTA CATLDKKQRN FDKVLAEWKQ
KLDESQAELE AAQKESRSLS TELFKMRNAY EEVVDQLETL RRENKNLQEE ISDLTEQIAE
TGKNLQEVEK TKKLVEQEKS DLQVALEEVE GSLEHEESKI LRVQLELSQV KSELDRKVIE
KDEEIEQLKR NSQRATEAMQ SVLDAEIRSR NDALRVKKKM EGDLNEMEIQ LGHSNRQVAE
TQKHLRTVQG QLKDSQLHLD DALRSNEDLK EQLAIVERRN GLLLEELEEM KVALEQTERT
RRLSEQELLD ASDRVQLLHS QNMSLINTKK KLEADIAQCQ AEVENSIQES RNAEEKAKKA
ITDAAMMAEE LKKEQDTSAH LERMKKNLEQ TVKALQHRLD EAEQLALKGG KKQIQKLENR
VRELENELDV EQKRGAEALK GAHKYERKVK EMTYQADEDR KNILRLQDLV DKLQAKVKSY
KRQAEEAEEQ ANTQLSRCRR VQHELEEAAE RADIAESQAN KLRAKSRDVG GQ
//
