ID G7NPW3_MACMU Unreviewed; 435 AA.
AC G7NPW3;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 22-FEB-2023, entry version 25.
DE SubName: Full=Plasma kallikrein-like protein 4 {ECO:0000313|EMBL:EHH31715.1};
GN ORFNames=EGK_12842 {ECO:0000313|EMBL:EHH31715.1};
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544 {ECO:0000313|EMBL:EHH31715.1};
RN [1] {ECO:0000313|EMBL:EHH31715.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CR-5 {ECO:0000313|EMBL:EHH31715.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001272; EHH31715.1; -; Genomic_DNA.
DR AlphaFoldDB; G7NPW3; -.
DR MEROPS; S01.992; -.
DR Proteomes; UP000013456; Chromosome 20.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001254; Trypsin_dom.
DR PANTHER; PTHR24250; CHYMOTRYPSIN-RELATED; 1.
DR PANTHER; PTHR24250:SF45; INACTIVE SERINE PROTEASE 54; 1.
DR Pfam; PF00089; Trypsin; 1.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
PE 4: Predicted;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..435
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003501463"
FT DOMAIN 25..310
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
FT REGION 362..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..383
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 435 AA; 48282 MW; 4A644A3C8D2F5B03 CRC64;
MRGVLLVLLG LLHSSTSCGV QKASVFYGPD LKEGLVSSME FPWVVSLQDS QYTHLAFGCI
LSEFWVLSIA SAIQNRPVPL LLGPAASPRN IYFLLGPDQN YVSALTTPNY IVDSQHYWRK
DIVVIVGISN MDPSKIAHTE YPVNTIIIHE DFDNNSMSNN IALLKTDTAM HFGNLVQSIC
FLGRKLHTPP VLQNCWVSGW NPTSAVKAFL LPEEATGNHM TMSILRKIFV KDLDICPLHK
LQKTECGSHT KEETKTACLG DPGSPMMCQL QQFDLWVLRG VLNFGGETCP GLFLYTKVED
YSKWITSKAE RAGPPLSSLH HWEKLISFSH HGPNAAMTQN SDSELGHVGS YLQGQGRTIT
HSRLATSSRD DLDVREKGVK ESGRSPEASV QPLYYDYYGG ELTGARALPV TLPYSKSAGF
VEKQKDPWRL CTCME
//
