ID   G7P036_MACFA            Unreviewed;       453 AA.
AC   G7P036;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Lariat debranching enzyme C-terminal domain-containing protein {ECO:0000259|SMART:SM01124};
GN   ORFNames=EGM_11063 {ECO:0000313|EMBL:EHH51642.1};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1] {ECO:0000313|EMBL:EHH51642.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CE-4 {ECO:0000313|EMBL:EHH51642.1};
RX   PubMed=22002653; DOI=10.1038/nbt.1992;
RA   Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA   Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA   Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA   Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA   Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA   Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT   "Genome sequencing and comparison of two nonhuman primate animal models,
RT   the cynomolgus and Chinese rhesus macaques.";
RL   Nat. Biotechnol. 29:1019-1023(2011).
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DR   EMBL; CM001277; EHH51642.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7P036; -.
DR   Proteomes; UP000009130; Chromosome 2.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR007708; DBR1_C.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR12849:SF0; LARIAT DEBRANCHING ENZYME; 1.
DR   PANTHER; PTHR12849; RNA LARIAT DEBRANCHING ENZYME; 1.
DR   Pfam; PF05011; DBR1; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   SMART; SM01124; DBR1; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   4: Predicted;
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          150..289
FT                   /note="Lariat debranching enzyme C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01124"
FT   REGION          302..374
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          386..439
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        353..374
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        418..439
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   453 AA;  50797 MW;  B1CD5D3211CDAAB3 CRC64;
     MRVAVAGCCH GELDKIYETL ALAERRGPGP VDLLLCCGDF QAVRNEADLR CMAVPPKYRH
     MQTFYRYYSG EKKAPVLTLF IGGNHEASNH LQELPYGGWV APNIYYLGLA GVVKYRGVRI
     GGISGIFKSH DYRKEVENNT LGSPAASELL EHLKPTYWFS AHLHVKFAAL MQHQILEIEH
     DPSAPDYLEY DIEWLTILRA TDDLINVTGH LWNMPENNGL HARWDYSATE EGMKEVLEKL
     NHDLKVPCNF SVTAACYDPS KPQTQMQLIH RINPQTTEFC AQLGITDINV RLQKSKEEHH
     VCGEYEEQDD VESNDSGEDR SEYNTDTSAL SSINPDEIML DEEEEDEDSI VSAHSDMNTP
     SVEPSDQTSE FSASFSDVRI LPGSMIVSSD DTVDSTVDRE GKPGGTVESG NGEDLTKVSL
     KRLSDEHEPE QRKKIKRRNQ AIYAAVDDDD DAA
//