ID G7P454_MACFA Unreviewed; 399 AA.
AC G7P454; A0A2K5UTT9;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Decaprenyl diphosphate synthase subunit 2 {ECO:0000313|Ensembl:ENSMFAP00000015870.1};
GN Name=PDSS2 {ECO:0000313|Ensembl:ENSMFAP00000015870.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000015870.1, ECO:0000313|Proteomes:UP000233100};
RN [1] {ECO:0000313|Ensembl:ENSMFAP00000015870.1, ECO:0000313|Proteomes:UP000233100}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMFAP00000015870.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR RefSeq; XP_005552289.1; XM_005552232.2.
DR SMR; G7P454; -.
DR STRING; 9541.ENSMFAP00000015870; -.
DR Ensembl; ENSMFAT00000066399.2; ENSMFAP00000015870.1; ENSMFAG00000031137.2.
DR Ensembl; ENSMFAT00000096522.1; ENSMFAP00000047923.1; ENSMFAG00000031137.2.
DR GeneID; 102119719; -.
DR KEGG; mcf:102119719; -.
DR CTD; 57107; -.
DR VEuPathDB; HostDB:ENSMFAG00000031137; -.
DR eggNOG; KOG0776; Eukaryota.
DR GeneTree; ENSGT00940000153498; -.
DR OMA; HEQVRWT; -.
DR OrthoDB; 2899987at2759; -.
DR Proteomes; UP000233100; Chromosome 4.
DR Bgee; ENSMFAG00000031137; Expressed in adult mammalian kidney and 13 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:1990234; C:transferase complex; IEA:Ensembl.
DR GO; GO:0097269; F:all-trans-decaprenyl-diphosphate synthase activity; IEA:Ensembl.
DR GO; GO:0052923; F:all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity; IEA:Ensembl.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
DR GO; GO:0000010; F:trans-hexaprenyltranstransferase activity; IEA:Ensembl.
DR GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0050878; P:regulation of body fluid levels; IEA:Ensembl.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:Ensembl.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR PANTHER; PTHR12001:SF55; ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 399 AA; 44025 MW; 8EE66E8D0B0D0506 CRC64;
MNLRQLLLHL PRYLGASGSP RRLWWSPSLD TISSVGSWRG QSSKSPAHWN QVVSEAEKIV
GYPTSFMSLR CLLSDELSNI AMQVRKLVGT QHPLLTTARG LVHDSRNSLQ LRGLVVLLIS
KAAGPSSVNT SCQNYDMVSG IYSCQRSLAE ITELIHTALL VHRGIVNLNE LQSSDGPLKD
MQFGNKIAIL SGDFLLANAC NGLALLQNTK VVELLASALM DLVQGVYHEN STSKESYITD
DIGISTWKEQ TFLSHGALLA KSCQAAMELA KHDAEVQDMA FQYGKHMAMS HKINSDVQPF
IKEKTSDSMT FNLNSAPVVL HQEFLGRDLW IKQIGEAQEK GRLDYAKLRE RIKAGKGVTS
AIDLCRYHGN KALEALESFP PSEARSALEN IVFAVTRFS
//
