ID G7P6B3_MACFA Unreviewed; 516 AA.
AC G7P6B3;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Interferon alpha/beta receptor 2 {ECO:0000313|EMBL:EHH53981.1};
GN ORFNames=EGM_14708 {ECO:0000313|EMBL:EHH53981.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH53981.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH53981.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001280; EHH53981.1; -; Genomic_DNA.
DR AlphaFoldDB; G7P6B3; -.
DR eggNOG; ENOG502S60E; Eukaryota.
DR Proteomes; UP000009130; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR PANTHER; PTHR20859:SF84; INTERFERON ALPHA_BETA RECEPTOR 2; 1.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR Pfam; PF09294; Interfer-bind; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:EHH53981.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 15..118
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF01108"
FT DOMAIN 133..229
FT /note="Interferon/interleukin receptor"
FT /evidence="ECO:0000259|Pfam:PF09294"
FT REGION 349..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 516 AA; 57721 MW; C005C709149838C6 CRC64;
MLLSQNAFIV RPLNLFLMVC ISLVFGISHD LPDYTSESCT FKISLRNFRS ILSWELKNHS
IVATHYKLLY TIMSKPEDLK IVKNCANTTR SFCDLTDEWR SIHEAYVTSL EGFSGNTTLF
NCSHNFWLDI DMSFEPPEFE IVGFTNHINV IVKFPSIVEE ELQFDLSLVI EEQSEGIVKK
HKPTIKGNMS GNFTYIIDKL IPNTNYCVSV YFDHNDEQAV IKSPLKCTLL QPGQESESAE
SAKVGGIITV FLIALVLIST IVTLKWIGYI CLRNSLPKVL NFHNFLACPF PNLPPLEAMD
IVEVIYINRK KKVWDYNYDD ESDSDTEAAL RTSGGGYTMH GLTVRPLGQT SATSTESQFT
DPDSEEEPDL PEVDVELPTT PKCSPQRLEL LSAPCERRAS PLQDPFPEED YSSTEGSGGR
ITFNVDLNSV FLRVLDDEDS DDLEEAPLMV SSHPEEMVDP EDPDNVQSSH LLASGEGTQP
TFPSPSSEGL QSEDAPSDQS ETSESDVDLG DGYIMR
//
