ID G7P6J9_MACFA Unreviewed; 455 AA.
AC G7P6J9;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=IF rod domain-containing protein {ECO:0000259|PROSITE:PS51842};
GN ORFNames=EGM_14811 {ECO:0000313|EMBL:EHH54067.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH54067.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH54067.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; CM001280; EHH54067.1; -; Genomic_DNA.
DR AlphaFoldDB; G7P6J9; -.
DR eggNOG; ENOG502QUS8; Eukaryota.
DR Proteomes; UP000009130; Chromosome 5.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF349; KERATIN, TYPE I CYTOSKELETAL 18; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}.
FT DOMAIN 105..416
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 109..143
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 214..294
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 321..408
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 455 AA; 51058 MW; A6CE667A774294F6 CRC64;
MKNPSSRRHR SAKPESCRLI FLLYSISFTT RSTFSTNYRS LGSVQAPRYG TRPVSSAASV
YASARGSGSR ISVSRSTSLR GGMRSGGLAS GMAGGLAGMG GIQNEKETMQ SLNECLASYL
DRVKSLEMEN GKLESKIREH LEKKGPQVRD WSHYFKIIED LRAQIFATTV DNARIVLQID
NAPLAADDIR VKYETELAMR QSVENDIHGL RKVIDDTNVT QLQLETEIEA LKEELLFMKK
NHEEEVKGLQ AQIASSGLTV EVDAPKSQDL AKIMVDIRAQ YDELARKNRE ELDKYWSQQI
EESTTVVTTQ SAEVGAAEMM LTKLRRTVQS LEIDLDSMRN LKASLENSLR EVEARYALQM
EQLNGILLHL ESELAQTRAE GQRQAQEYEA LLNIKVKLEA EIATYRRLLE DGEEFNLGDA
LDSSNSMQTI QKTTTRQIVD GKVVSETNDT KVLRH
//
