ID G7P8G6_MACFA Unreviewed; 493 AA.
AC G7P8G6;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Amyloid beta precursor protein binding family B member 3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=EGM_15458 {ECO:0000313|EMBL:EHH54587.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH54587.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH54587.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001281; EHH54587.1; -; Genomic_DNA.
DR AlphaFoldDB; G7P8G6; -.
DR eggNOG; ENOG502QR5N; Eukaryota.
DR Proteomes; UP000009130; Chromosome 6.
DR GO; GO:0001540; F:amyloid-beta binding; IEA:InterPro.
DR CDD; cd01272; PTB1_Fe65; 1.
DR CDD; cd01271; PTB2_Fe65; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR InterPro; IPR039576; APBB1/2/3.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR14058; AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B; 1.
DR PANTHER; PTHR14058:SF10; AMYLOID-BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 3; 1.
DR Pfam; PF00640; PID; 1.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00462; PTB; 2.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01179; PID; 2.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
FT DOMAIN 29..61
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 119..261
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT DOMAIN 297..422
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
SQ SEQUENCE 493 AA; 53260 MW; 8B1F0214AFFFD265 CRC64;
MLGKDYMLAI ILVNCDDDLW GDQSLEGEPG LPPGWRKIHD AAGTYYWHVP SGSTQWQRPA
WELGDAEDPG TGTEGIWGLR PLKGRSFSSL ESSLDRSNSL SWCGEESYIQ NMEPGAKCFA
VRSLGWVEVP EEDLAPGKSS IAVNNCIQQL AQTRSQSQPL DGAWGEGQNM LMILKKDAMS
LVNPLDHSLI HCQPLVHIRV WGVGSSKGRP SPISAPARDF AFVASDKDSC MLKCHVFRCD
VPAKVIASAL HGLCAQILSE RVGVSVDASC CSPDPISPED LPRQVELLDA VSQAAQKYEA
LYMGTLPVTK AMGMDVLNEA IGTLTTRGDR NAWVPTMLSV SDSLMTAHPI QAEASTEEEP
LWQCPVRLVT FIGVGRDPHT FGLIADLGRQ SFQCAAFWCQ PHAGGLSEAV QAACMVQYQK
CLVASAARGK AWGAQARARL RLKRTSSMDS PGGPLPLPLL KGGVGGAGAT PRKRGVFSFL
DAFRLKPSLL HMP
//
