ID G7PWT0_MACFA Unreviewed; 447 AA.
AC G7PWT0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=EGM_08868 {ECO:0000313|EMBL:EHH58903.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH58903.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH58903.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
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DR EMBL; CM001293; EHH58903.1; -; Genomic_DNA.
DR AlphaFoldDB; G7PWT0; -.
DR eggNOG; KOG2113; Eukaryota.
DR Proteomes; UP000009130; Chromosome 18.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22424; KH-I_MEX3_rpt2; 1.
DR CDD; cd16722; RING-HC_MEX3C; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047226; KH-I_MEX3_rpt2.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR047227; MEX3.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR23285; RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR23285:SF8; RNA-BINDING E3 UBIQUITIN-PROTEIN LIGASE MEX3C; 1.
DR Pfam; PF00013; KH_1; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00322; KH; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50084; KH_TYPE_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00117}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 396..436
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 301..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 48102 MW; 11973CB3CF8DC3E3 CRC64;
MMAAMLSHAY GPGGCGAAAA ALNGEQAALL RRKRASTPPS CKIKALRAKT NTYIKTPVRG
EEPIFVVTGR KEDVAMAKRE ILSAAEHFSM IRASRNKNGP ALGGLSCSPN LPGQTTVQVR
VPYRVVGLVV GPKGATIKRI QQQTHTYIVT PSRDKEPVFE VTGMPENVDR AREEIEMHIA
MRTGNYIELN EENDFHYNGT DVSFEGGTLG SAWLSSNPVP PSRARMISNY RNDSSSSLGS
GSTDSYFGSN RLADFSPTSP FSTGNFWFGD TLPSVGSEDL AVDSPAFDSL PTSAQTIWTP
FEPVNPLSGF GSDPSGNMKT QRRGSQPSTP RLSPTFPESI EHPLARRVRS DPPSTGNHVG
LPIYIPAFSN GTNSYSSSNG GSTSSSPPES RRKHDCVICF ENEVIAALVP CGHNLFCMEC
ANKICEKRTP SCPVCQTAVT QAIQIHS
//
