ID   G7Q1E5_MACFA            Unreviewed;       373 AA.
AC   G7Q1E5;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 71.
DE   RecName: Full=Glucose-fructose oxidoreductase domain-containing protein 2 {ECO:0000256|ARBA:ARBA00040293};
GN   Name=ENKD1 {ECO:0000313|Ensembl:ENSMFAP00000039328.2};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|Ensembl:ENSMFAP00000039328.2, ECO:0000313|Proteomes:UP000233100};
RN   [1] {ECO:0000313|Ensembl:ENSMFAP00000039328.2, ECO:0000313|Proteomes:UP000233100}
RP   NUCLEOTIDE SEQUENCE.
RA   Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSMFAP00000039328.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Promotes matrix assembly. {ECO:0000256|ARBA:ARBA00037474}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498}.
CC   -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family.
CC       {ECO:0000256|ARBA:ARBA00010928}.
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DR   AlphaFoldDB; G7Q1E5; -.
DR   STRING; 9541.ENSMFAP00000039328; -.
DR   Ensembl; ENSMFAT00000013590.2; ENSMFAP00000039328.2; ENSMFAG00000031412.2.
DR   VEuPathDB; HostDB:ENSMFAG00000040849; -.
DR   eggNOG; KOG2742; Eukaryota.
DR   GeneTree; ENSGT00940000153866; -.
DR   OrthoDB; 2899892at2759; -.
DR   Proteomes; UP000233100; Chromosome 20.
DR   Bgee; ENSMFAG00000031412; Expressed in pituitary gland and 13 other cell types or tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43818; BCDNA.GH03377; 1.
DR   PANTHER; PTHR43818:SF8; GLUCOSE-FRUCTOSE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000233100};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          20..97
FT                   /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01408"
SQ   SEQUENCE   373 AA;  40869 MW;  A421CBDAE345710B CRC64;
     MKMLPGVGVF GTAAPTGAEA LWGKTEEEAK QLAEEMNIAF YTSRTDDILL HQDVDLVCIS
     IPPPLTRQIS VKALGIGKNV VCEKAATSVD AFRMVTASRY YPQLMSLVGN VLRFLPAFVR
     MKQLISEHYV GAVMICDARI YSGSLLSPSY GWICDELMGG GGLHTMGTYI VDLLTHLTGR
     RAEKVHGLLK TFVRQNAAIR GIRHVTSDDF CFFQMLMGGG VCSTVTLNFN MPGAFVHEVM
     VVGSAGRLVA RGADLYGQKN SATQEELLLR DSLAVGAGLP EQGPQDVPLL YLKGMVYMVQ
     ALRQSFQGQG DRRTWDRTPV SMAASFEDGL YMQSVVDAIK RSSRSGEWEA VEVLTEEPDT
     NQNLCEALQR NNL
//