ID G7Q1M0_MACFA Unreviewed; 455 AA.
AC G7Q1M0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=C-type lectin domain family 18 member A {ECO:0008006|Google:ProtNLM};
GN ORFNames=EGM_11943 {ECO:0000313|EMBL:EHH60558.1};
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1] {ECO:0000313|EMBL:EHH60558.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CE-4 {ECO:0000313|EMBL:EHH60558.1};
RX PubMed=22002653; DOI=10.1038/nbt.1992;
RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT "Genome sequencing and comparison of two nonhuman primate animal models,
RT the cynomolgus and Chinese rhesus macaques.";
RL Nat. Biotechnol. 29:1019-1023(2011).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; CM001295; EHH60558.1; -; Genomic_DNA.
DR AlphaFoldDB; G7Q1M0; -.
DR eggNOG; KOG3017; Eukaryota.
DR eggNOG; KOG4297; Eukaryota.
DR Proteomes; UP000009130; Chromosome 20.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR CDD; cd05380; CAP_euk; 1.
DR CDD; cd00037; CLECT; 1.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 3.40.33.10; CAP; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 1.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR018378; C-type_lectin_CS.
DR InterPro; IPR014044; CAP_domain.
DR InterPro; IPR035940; CAP_sf.
DR InterPro; IPR001283; CRISP-related.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR000742; EGF-like_dom.
DR PANTHER; PTHR10334:SF521; C-TYPE LECTIN DOMAIN FAMILY 18 MEMBER A-RELATED; 1.
DR PANTHER; PTHR10334; CYSTEINE-RICH SECRETORY PROTEIN-RELATED; 1.
DR Pfam; PF00188; CAP; 1.
DR Pfam; PF00059; Lectin_C; 1.
DR PRINTS; PR00837; V5TPXLIKE.
DR SMART; SM00034; CLECT; 1.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00198; SCP; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 1.
DR SUPFAM; SSF55797; PR-1-like; 1.
DR PROSITE; PS00615; C_TYPE_LECTIN_1; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS50026; EGF_3; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Lectin {ECO:0000256|ARBA:ARBA00022734}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..455
FT /note="C-type lectin domain family 18 member A"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003503263"
FT DOMAIN 228..261
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 306..442
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DISULFID 251..260
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 455 AA; 50595 MW; 507271C18EE84152 CRC64;
MLHSETSPGR GHLLAVLLAF LGTTWAEVWP PQLQEQAPMA RALTRKESFL LLSLHNRLRS
WVQPPAADMR RLDWSDSLAQ LAQARAALCG TPTPSLASAP WRTLQVGWNV QLLPAGSASF
VEVVSLWFAE GQWYSHAAGE CARNATCTHY TQLVWATSSQ LGCGRHLCSA DQAATEAFVC
AYSPGGNWEV NGKTIVPYKK GAWCSLCTAS VSGCFKAWDH AGGLCEVPRN PCRMSCQNHG
RLNISTCHCH CPPGYTGRYC QVRCSLQCVH GRFREEECSC VCDVGYGGAQ CATKVHFPFH
TCDLRIDGDC FMVSSEADTY YRARMKCQRK GGVLAQIESQ KVQDILAFYL GRLETTNEVT
DSDFETRNFW IGLTYKTAKD SFRWATGEHQ AFTSFAFGQP DNQGLVWLRA AMGFGNCVEL
QASAAFNWND QRCKTRNRYI CQFAQEHISR WGPGS
//
