ID   G7SEJ7_STRSU            Unreviewed;      1009 AA.
AC   G7SEJ7;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   24-JAN-2024, entry version 55.
DE   SubName: Full=Serum opacity factor {ECO:0000313|EMBL:AER19904.1};
GN   ORFNames=SSUD12_1630 {ECO:0000313|EMBL:AER19904.1};
OS   Streptococcus suis D12.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1004952 {ECO:0000313|EMBL:AER19904.1, ECO:0000313|Proteomes:UP000008845};
RN   [1] {ECO:0000313|EMBL:AER19904.1, ECO:0000313|Proteomes:UP000008845}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D12 {ECO:0000313|EMBL:AER19904.1};
RX   PubMed=22026465; DOI=10.1186/1471-2164-12-523;
RA   Zhang A., Yang M., Hu P., Wu J., Chen B., Hua Y., Yu J., Chen H., Xiao J.,
RA   Jin M.;
RT   "Comparative Genomic Analysis of Streptococcus suis reveals significant
RT   genomic diversity among different serotypes.";
RL   BMC Genomics 12:523-523(2011).
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DR   EMBL; CP002644; AER19904.1; -; Genomic_DNA.
DR   RefSeq; WP_014638462.1; NC_017621.1.
DR   AlphaFoldDB; G7SEJ7; -.
DR   KEGG; ssk:SSUD12_1630; -.
DR   PATRIC; fig|1004952.3.peg.1590; -.
DR   HOGENOM; CLU_328147_0_0_9; -.
DR   Proteomes; UP000008845; Chromosome.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR019931; LPXTG_anchor.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR   NCBIfam; NF040483; serum_opaci_fac; 1.
DR   Pfam; PF00746; Gram_pos_anchor; 1.
DR   Pfam; PF00092; VWA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW   Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW   Secreted {ECO:0000256|ARBA:ARBA00022512}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           26..1009
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5038791284"
FT   DOMAIN          198..426
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   DOMAIN          974..1009
FT                   /note="Gram-positive cocci surface proteins LPxTG"
FT                   /evidence="ECO:0000259|PROSITE:PS50847"
FT   REGION          74..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          692..933
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          948..982
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        79..117
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        118..134
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        792..823
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        898..918
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        919..933
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1009 AA;  112387 MW;  89893C073E0602BE CRC64;
     MNHPKFTLRK LSIGLVSLGA GVALSGTLYP QNTVTVYAET PVTESTTLEK NEEIDNTSSI
     TRPIAVEDPK VVQANENKEG EAVDSSSTLD LPKSDEETTF PEALTNENAS ESEVKVAENT
     SSSEEKATEK EERAVQYVEK EVDDYSTNVE KPNETVSSTV DKTPKELFTV SRTAEVGQDG
     VVTVTTQIVP KEIDKGAEIV VLVDTSKKMD EEAKKTAKDN IIKLVEKMTD STNAHNSRNS
     VRVIGFNRKL SESKEVNKTN VTDTIDNLFY NAEQNYNWGV DMQGAIHEAR RILESENSGK
     RKHIVLLSQG ESTFSYDLTD DVKSKPTYKT IEENKVVHTN PLLPWPFTFD VTVRRANLLD
     DAKSLISFLN KVGITRFDKA LDDVSTIAGI TKLIGIIAKD PLDYINLVDV DSSQLEEKNF
     NYEKQIGEGY HFRSFYERKV EPLTFRNQIV SKIKHNLTTE LKKAELPTNT LSYIAEKLGL
     TNTSEKAIDL FANSLVDYIF YGRKNIFNNH NLSAQAEAKI ATKNGIHVYA VDVTKDKAGE
     EKNKNKFDEY LKKMSGDDKK FLSVDENVAE KFKDVLTKVT LVDTLEDNVE IVKEPKDPKV
     SIKKNSSTFW LSWITSSKTT ITWNLDKEDL IKAYQTNQPL SLSYQLQLKD KKKKDSQELV
     RTEVRYSLNN DREKTAKYSS LKVSLNHKTK KVSVPVPIEP QVPDKPIDMP KVENETPKGT
     PETPMQEKPN VPEATLPMQP ELPKETGKTG NNVEPESPKP IEDSTDDSAN KPDSTIPKAT
     DDIIIPDTSR PMKPESTDEI DHAKNNVEPE TPKLIEKPID DSANKPKLAT PKATDNIIIP
     NPTLPMKPET AEETEKLGNN VKPESPKPIE DTDSSAGTPK LDIPKVTDTP DLSPPMKPES
     TEEIDKAENS DTPDSSKTIK DSDNSAPIST IKDKVNAETV ANQVELAMNQ KSRLSENMEK
     VSSVNRSNEK SDTLPSTGQA DSPIYTLTAL SLLVGAQVLY RTKRKQESK
//