ID   G7UV06_PSEUP            Unreviewed;       473 AA.
AC   G7UV06;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Cardiolipin synthase {ECO:0000313|EMBL:AER55085.1};
GN   OrderedLocusNames=DSC_02160 {ECO:0000313|EMBL:AER55085.1};
OS   Pseudoxanthomonas spadix (strain BD-a59).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Pseudoxanthomonas.
OX   NCBI_TaxID=1045855 {ECO:0000313|EMBL:AER55085.1, ECO:0000313|Proteomes:UP000005870};
RN   [1] {ECO:0000313|EMBL:AER55085.1, ECO:0000313|Proteomes:UP000005870}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BD-a59 {ECO:0000313|EMBL:AER55085.1,
RC   ECO:0000313|Proteomes:UP000005870};
RX   PubMed=22207748; DOI=10.1128/JB.06436-11;
RA   Lee S.H., Jin H.M., Lee H.J., Kim J.M., Jeon C.O.;
RT   "Complete Genome Sequence of the BTEX-Degrading Bacterium Pseudoxanthomonas
RT   spadix BD-a59.";
RL   J. Bacteriol. 194:544-544(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP003093; AER55085.1; -; Genomic_DNA.
DR   RefSeq; WP_014159263.1; NC_016147.2.
DR   AlphaFoldDB; G7UV06; -.
DR   STRING; 1045855.DSC_02160; -.
DR   KEGG; psd:DSC_02160; -.
DR   eggNOG; COG1502; Bacteria.
DR   HOGENOM; CLU_038053_1_0_6; -.
DR   OrthoDB; 9762009at2; -.
DR   Proteomes; UP000005870; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008808; F:cardiolipin synthase activity; IEA:InterPro.
DR   GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:InterPro.
DR   CDD; cd09152; PLDc_EcCLS_like_1; 1.
DR   CDD; cd09158; PLDc_EcCLS_like_2; 1.
DR   Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR   InterPro; IPR022924; Cardiolipin_synthase.
DR   InterPro; IPR027379; CLS_N.
DR   InterPro; IPR025202; PLD-like_dom.
DR   InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR   NCBIfam; TIGR04265; bac_cardiolipin; 1.
DR   PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR   PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR   Pfam; PF13091; PLDc_2; 2.
DR   Pfam; PF13396; PLDc_N; 1.
DR   SMART; SM00155; PLDc; 2.
DR   SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR   PROSITE; PS50035; PLD; 2.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW   Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005870};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        38..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          214..241
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
FT   DOMAIN          386..413
FT                   /note="PLD phosphodiesterase"
FT                   /evidence="ECO:0000259|PROSITE:PS50035"
SQ   SEQUENCE   473 AA;  52675 MW;  B33706026FF38C65 CRC64;
     MTEPPSIGSW LLILDWVIRL AALAWIPSRT TPAAARSWLL LVFFVPLAGL PLYLLFGHPW
     LSRERVRRQA EASQLIREQQ KPLGELRWQP QGDGTDTEMV PLVERLGDFM PTHGNAVALL
     DDYEQSLRAL LEDIAGARER VHLLYYLMLD DRVGDMVCQA LLQAAARGVE CRLMLDAVGA
     KRGIGAYARR LRAGGVQVQK LLPGGLRWRR SGRIDLRNHR KIAVIDNRAG YVGSQNLADP
     GGFVRGYPNR ELVARVEGPA VSHLEAVFAS DWYLETGQRL EVIATTPVRD ANVAAQLLPS
     GPAYPFSNAR DVVCALIHLA QKKLVLTTPY FVPDDGTLSA LRIAALSGVD TQLILSASNN
     QQLTTWAQES YYSELLQSGV KIAHYRPHFL HAKHLSVDDH MALVGSMNLD IRSFALNAEI
     GMLCYDQGVV ARMRQIEADY LAHSDVLTLE AWNRRPAWKR SREGIARLAD SFI
//