ID G7XYD1_ASPKW Unreviewed; 636 AA.
AC G7XYD1;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=FAD monooxygenase {ECO:0000313|EMBL:GAA91927.1};
GN ORFNames=AKAW_10041 {ECO:0000313|EMBL:GAA91927.1};
OS Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus
OS awamori var. kawachi).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1033177 {ECO:0000313|EMBL:GAA91927.1};
RN [1] {ECO:0000313|EMBL:GAA91927.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IFO 4308 {ECO:0000313|EMBL:GAA91927.1};
RX PubMed=22045919; DOI=10.1128/EC.05224-11;
RA Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., Takashita H.,
RA Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.;
RT "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, used
RT for brewing the Japanese distilled spirit shochu.";
RL Eukaryot. Cell 10:1586-1587(2011).
CC -!- SIMILARITY: Belongs to the PheA/TfdB FAD monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007801}.
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DR EMBL; DF126486; GAA91927.1; -; Genomic_DNA.
DR AlphaFoldDB; G7XYD1; -.
DR STRING; 1033177.G7XYD1; -.
DR VEuPathDB; FungiDB:AKAW_10041; -.
DR eggNOG; KOG3855; Eukaryota.
DR InParanoid; G7XYD1; -.
DR Proteomes; UP000006812; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR CDD; cd02979; PHOX_C; 1.
DR Gene3D; 3.40.30.20; -; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012941; Phe_hydrox_C_dim_dom.
DR InterPro; IPR038220; PHOX_C_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43004:SF7; P-HYDROXYBENZOATE-M-HYDROXYLASE; 1.
DR PANTHER; PTHR43004; TRK SYSTEM POTASSIUM UPTAKE PROTEIN; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR Pfam; PF07976; Phe_hydrox_dim; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000313|EMBL:GAA91927.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 9..367
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
FT DOMAIN 412..588
FT /note="Phenol hydroxylase C-terminal dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07976"
SQ SEQUENCE 636 AA; 70956 MW; F35D488ADBF2EA51 CRC64;
MAPSQQEKYD IVIVGAGPVG IVLSLCMSRW GYKVKHIDNR PVPTATGRAD GIQPRSTEIL
RNLGLKRQIM AFKPAKVYDV AFWDPLPGGQ GIHRTGSWPS CPRFIDTRYP FTTLVHQGKI
ERVFLDEIEK AGTTVERPWT IVGFKNDGLD ETYPVEVQLK SIDTNVIETV RTKYLFSGEG
ARSFIRQQLG IQIQYKDPIS YVWGVMDGVV RTNFPDIETK CTIHSDAGSI MVIPREDNMV
RLYVQIASSD DPDFDPRKTA TSEDVQATAR KILQPYWVEW DRVEWYSVYP IGQGISEKYT
LDERVFMGGD ACHTHSPKAG QGMNTAFHDA LNMAWKLHAV ESGLAKRSIL STYETERKDI
AETLLSFDNK YAALFSKRRP TAGEVGEASH TTAAAGGEED EFVKTFKSSC EFTSGYGVAY
KPNVFTWDAS HPAQSPLFDV PGVRLTPGRA FTPTTVTRLA DSNHVHLEQE IPANGAFRIF
IFAGKQDKTS KAITDLAANL EKERSFLSVY RRSDIADVSF FENHLPHSKL FSICLIYAGE
KNQIDVDSIP KILRDYHHHL YADNIPDVRV PQATYAAHEK LGFDVEKGGV VVTRPDSHVA
CTVQLSEGSG TVDALNAFFG SFSTKPLGQD SQHSRL
//
