ID   G7YAQ4_CLOSI            Unreviewed;       674 AA.
AC   G7YAQ4;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Ras-related protein Rab-33B {ECO:0000313|EMBL:GAA50038.1};
GN   ORFNames=CLF_103956 {ECO:0000313|EMBL:GAA50038.1};
OS   Clonorchis sinensis (Chinese liver fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX   NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA50038.1, ECO:0000313|Proteomes:UP000008909};
RN   [1] {ECO:0000313|EMBL:GAA50038.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Henan {ECO:0000313|EMBL:GAA50038.1};
RX   PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA   Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA   Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA   Yu X.;
RT   "The draft genome of the carcinogenic human liver fluke Clonorchis
RT   sinensis.";
RL   Genome Biol. 12:R107-R107(2011).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Henan;
RA   Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA   Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA   Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA   Wu Z., Yu X.;
RT   "The genome and transcriptome sequence of Clonorchis sinensis provide
RT   insights into the carcinogenic liver fluke.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC       {ECO:0000256|ARBA:ARBA00006270}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DF143008; GAA50038.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7YAQ4; -.
DR   Proteomes; UP000008909; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   NCBIfam; TIGR00231; small_GTP; 1.
DR   PANTHER; PTHR47978; -; 1.
DR   PANTHER; PTHR47978:SF52; INTRAFLAGELLAR TRANSPORT PROTEIN 27 HOMOLOG; 1.
DR   Pfam; PF00071; Ras; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00175; RAB; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51419; RAB; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT   REGION          651..674
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          5..171
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   674 AA;  76680 MW;  22899BC83CD5297F CRC64;
     MPKLVTEFES MIQQASKEID DMQKSMHQLE CKLESNTTAY HQSLDQAYSE LESKIRQAEE
     MSKARANRKT EQLRQTQAQE TEQIEILRKE NDKLTEALEE VESSVEESKH TIEDLQTTAR
     VEQAKREKAD AFTCKRIQIE CEELMRKLDQ LRELNRRLRD ERDEALNDDR ARKLISTNSL
     MDEVNEVFER QNVCAEEGTE MTAQVLQSGE ITSPQDAVVT ATEVFSDEDY EFEDSWSQSV
     DSFKLNKSIY EAERPEGTDQ LQKPQQAAVR EEVFGCSFTK IKNSDIVVAA DGMNAQPSSS
     THWICDWTLS LQDKFLLDTT AAQANVSSDA RHLASLVLRY MVARNFLTRD HQAAFWLAGH
     HFDHIFTFRQ DIPRKSVNKI RPLYVFRLLG VCDRTVSSPI ASLQNVVSPL WFNFVNDEVM
     RRTLEDLYNP GVQISGQPTE LGRGLRMFKV VVVGQSGSGR TALVSRICGD KEIDKAEEVR
     EEIELRVCSL EVDGERVVIQ FWDIQGDDKY FPVNQYICEK ADGVIFVYAG CSMSDFNQLD
     HRIMKMLKGL KTTKKLWEDT VNVLWANKWD LVNSSPALLP VPRSSAEGLA KHGCTLWKEF
     SASVARRIIA ACNAGHHFEL AALSRETYQY MPNDRTAYSG STVNLVDISP GQEDDCSKEN
     EANVKSTAFT ATDN
//