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Database: UniProt
Entry: G7YBB9_CLOSI
LinkDB: G7YBB9_CLOSI
Original site: G7YBB9_CLOSI 
ID   G7YBB9_CLOSI            Unreviewed;       441 AA.
AC   G7YBB9;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   25-OCT-2017, entry version 20.
DE   SubName: Full=Voltage-gated hydrogen channel 1 {ECO:0000313|EMBL:GAA50253.1};
GN   ORFNames=CLF_104291 {ECO:0000313|EMBL:GAA50253.1};
OS   Clonorchis sinensis (Chinese liver fluke).
OC   Eukaryota; Metazoa; Platyhelminthes; Trematoda; Digenea;
OC   Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX   NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA50253.1, ECO:0000313|Proteomes:UP000008909};
RN   [1] {ECO:0000313|Proteomes:UP000008909}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L.,
RA   Lv X., Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C.,
RA   Hu X., Xu J., Yu X.;
RT   "The draft genome of the carcinogenic human liver fluke Clonorchis
RT   sinensis.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Henan;
RA   Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA   Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA   Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C.,
RA   Xu J., Wu Z., Yu X.;
RT   "The genome and transcriptome sequence of Clonorchis sinensis provide
RT   insights into the carcinogenic liver fluke.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DF143027; GAA50253.1; -; Genomic_DNA.
DR   InParanoid; G7YBB9; -.
DR   Proteomes; UP000008909; Unassembled WGS sequence.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0030171; F:voltage-gated proton channel activity; IEA:InterPro.
DR   InterPro; IPR031846; Hvcn1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   PANTHER; PTHR12305:SF47; PTHR12305:SF47; 2.
DR   Pfam; PF00520; Ion_trans; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008909};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008909};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     75     94       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    200    222       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    259    277       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      196    281       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   441 AA;  50450 MW;  74C4F8673015598A CRC64;
     MLKWCFYSRV CLKVEIWYGY DFDWSRNRAI LKQLVKDNID ISMLKDEMST TLQQRGRKTW
     RQYLLTILRS HMMQIILSLL VLLDAGIVIT EIVLEIQSLQ KANAQLNHTP SKSGAALRRT
     RKYSKIILHR QRNGTHLQTF SEIHRQPRNY TTPTTPNIAL SDVQIDRLGE ENIFAHDPLS
     FTHGTNVDNS AQMMHEASEV LHYLSIAITG LFLICVIIKI ICLKRKFLRD TNEYFDAGII
     MASFASDVLY VRYASETAAA MVVFLLWRII RIINALMMHK QQQYELRIAM QKRARRLLGR
     KMEIIRTEKE MQDKHIGALE DLLRELGASA EVIRRCKPRY KKCTKEQTNN ALKSIAALTT
     GVMGGLVGAP SNFQGVISKY GGTGINTPTA SQKSLQDTDL AVGMFRFVGA HEQQFWQHPD
     KDLPTELPPS VQKPEKGQPF A
//
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