ID   G7YC33_CLOSI            Unreviewed;      1019 AA.
AC   G7YC33;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   28-JUN-2023, entry version 35.
DE   SubName: Full=Tetratricopeptide repeat protein 12 {ECO:0000313|EMBL:GAA50517.1};
GN   ORFNames=CLF_104674 {ECO:0000313|EMBL:GAA50517.1};
OS   Clonorchis sinensis (Chinese liver fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX   NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA50517.1, ECO:0000313|Proteomes:UP000008909};
RN   [1] {ECO:0000313|EMBL:GAA50517.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Henan {ECO:0000313|EMBL:GAA50517.1};
RX   PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA   Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA   Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA   Yu X.;
RT   "The draft genome of the carcinogenic human liver fluke Clonorchis
RT   sinensis.";
RL   Genome Biol. 12:R107-R107(2011).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Henan;
RA   Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA   Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA   Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA   Wu Z., Yu X.;
RT   "The genome and transcriptome sequence of Clonorchis sinensis provide
RT   insights into the carcinogenic liver fluke.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DF143054; GAA50517.1; -; Genomic_DNA.
DR   AlphaFoldDB; G7YC33; -.
DR   Proteomes; UP000008909; Unassembled WGS sequence.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR043195; TTC12.
DR   PANTHER; PTHR46540; TETRATRICOPEPTIDE REPEAT PROTEIN 12; 1.
DR   PANTHER; PTHR46540:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 12; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT   REGION          313..369
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          827..856
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          904..928
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        347..363
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        827..855
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        909..926
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1019 AA;  110040 MW;  D60FB4024AC582ED CRC64;
     MKPLYSKLSE KPTNISKVKH PVKVILSNCT KLINDLAFSK TFINTANSEM KPFGEGQQPN
     SMSVEAFKLA VEKDAAERAE RRARQRSRAE KLKERANTFF KAGNWRRAAD LYSKAIEVCK
     DWEILYTNRA QAYLRSGDAN AALADCDTAL KLLEFRQSAT TNSAEFGASI VPNPQVAKTH
     FHRGKALMAL GKPEEALLAY EQSRAFSLSS KPISGGSVNS PWPAYLVEYV AQAEAAVAAK
     QADARAEAEF EARAIRPEST GDGSQMSSVP SSQQLVCLLA QLARANQDQA YYSAGLRQLI
     RLFDSVPREQ PTVQIPNVEV PPTEERNKPE SNPSRSNRRG RKKKQSGSAH QTALQTNKNV
     PSKKSDPVPV ETFTDLQTLF RLKNGFTLLG REVNEICKDL DQLSSTGDSA KTTSEPVLQP
     VNKTDSKQGD LTDRLLALLN LTSLLTRDCG ENQRILVVQL PGLIQMALKC TILSTDFVAQ
     VVNQLSDNSL SEKISGSRSS FEARTRHKLE ALRSAASDLL VTLTSQPSGR QALLSAVGSS
     SLLDAIAVCL AESLGQTLLT PLSNGTTGRP VGADMKARLS VSEVNRRASL NSNSSSAISA
     ICAARAARLL ENLTESPGFL LSARSSVSNL ESLLSLIEAA VSVTNRNNRS ITTTARCLAS
     LLDGLSAACH DTSLRTNILQ RRQPLLTALA ECLTQHAPLL TDPEHALLVG STCRLLHNIC
     VGSLGPGSTA SPNSLSTVLN ASGRLADTLL AGVGVVLDQP GHGPELRAVA TALAGRLLPL
     CSAERILSWL NEPDDSPIQA NGQHPNNLPS DRSRLLLAIL DSCSIPNSGH KSHHTNGGQS
     KEDPTLSSTS DSNRDQDHQL SAHMLSGCIR CLAAATNHSV RMRYFIGDDR RRVRRLARVI
     RAKLPPSSGG VPPQNSLKSS VCSGPTQPRD EPLAGNACLI LQHCCDDTPL AEHLQGTSVI
     LDLLQLIQES QQLDTKRNAA ILIGKLAQAS HAHRDELTRL DGWSVLTPFN SWNAALDRM
//