ID G7YIH2_CLOSI Unreviewed; 1514 AA.
AC G7YIH2;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 28-JUN-2023, entry version 26.
DE SubName: Full=RUN and SH3 domain-containing protein 1 {ECO:0000313|EMBL:GAA52755.1};
GN ORFNames=CLF_108767 {ECO:0000313|EMBL:GAA52755.1};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA52755.1, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA52755.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA52755.1};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DF143347; GAA52755.1; -; Genomic_DNA.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR CDD; cd17685; RUN_RUSC; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR047343; RUSC1_2.
DR PANTHER; PTHR15591; RUN AND SH3 DOMAIN CONTAINING; 1.
DR PANTHER; PTHR15591:SF13; RUN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM00593; RUN; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR PROSITE; PS50826; RUN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT DOMAIN 1111..1260
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT REGION 201..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 541..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 684..717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 863..958
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1032..1057
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1268..1307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1324..1514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 387..414
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..462
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 868..890
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 907..931
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 932..958
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1034..1053
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1269..1303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1365..1483
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1514 AA; 164161 MW; C4E4C83DA35AA154 CRC64;
MYDPLSAYAT YCFPAREDTY PRNDLSSRTK PPVLMNSNDL TDHQIDMLQH NDVNQFDSSD
PNSVGSNAPM VSSVWLEQGD YFFDDEFSVP FDTNLQDDLV QNELNMNGMT VSLGPTVPPS
RTNLQLEQSR SDSCICTPGD SGESGLISAN PEQLVPPYLS EPPRRHPQLM GAMQNTPVTP
SQNGAIYEST NGVVQSELNR VDTESDSGHH KRDFQSSGVS QPSPNASQFS GQSGSTSWMQ
MVMERSCNPD LKALLSRAAM AVDYKLAYGE LLPIDSSTGS LVQQLIRKRF DERPNNCSRG
LARSLSQGDL LTAASLAGLR YALDQAAQCL PRTDKRSIEG RSAGVTERGE SVGSPNISDS
AEAGAPNTTT WAKRHGSRES LKRKFLNTKE PTTTPQVPAV SDTSNKLETS DQPENVNPWR
MMKQAHGTLI TWNQLKRTLK TGQPLERGPH TRESRREQHG RRACDVVSEQ VNTGGTDLCV
TSDTQLLENA YSRPTCRSRS QPVSANHYMY RFSGTLLEIF MRAKADEGAV RCVYNTSSDL
GDNLDSATRM RSSAADPRPT GSSSQMPATA VRIGHRRSVG SGTEPTKLLS ETDKHPLLRG
DRILPQRFQP PDLSTTSSSG EQSNNRFTRH FGAQFPSLDA YTQADTTVAP NPLRCSSPVW
SPSLPTRCSV GGIKPSHYAF IRHSHPRHSS RPQSFDPSRT AIPHKTPLVD DKSSDPSPEL
ATCLTASVGP DSPYMAALRA DYMADGYSAG WLGNPRASIA YPGLGLLSIP RPSRLTGAAF
LSHTLPDLSF LGKAGAEEER KGTPTMPKRV ASCRFHGRVT NGHCGAKCAC RSVPAGRNGT
PAWLHPRSRL TGKPRRPELK AYTFSPDLTD VLDQSNNDVS PNNAQNHTDE KPSIPDIVPI
HRFGASDSSD ADSRLRPHLS HRLRYKVDRS TSEPELNSTS RLTFRSTGDD QSYENPSALL
TSSGQNCYGW DDNNSSNKSY DLFTPHGRRP KKSVSFSGKI RLLRVQNGVE SPTSPEPKVI
PRNWGLYGQE TPLAEFNPRN SPGRDTNQPG EVPRQSDVDV RYHAMVNDVI KAVQETVAYY
STATSGNPDP AGNGCNAADP LPYSAIAALG SAGRQPLLAV VAPLTVLLSD GLLPPTKPIF
ITKPRTRLWQ MVEESCRPGP LLSGVAYRVL SDAVSQVKAL TSITLEKVKF KAFICACLNA
KALPMWLNAV VANESLLSRF YCEDAFVRQC RATQRGLHAD LLTHLEQLLA YPFNLDLAVE
VRKPLFTDPS TGANRNLGSQ STGAAPATTS SPLVLNSTQQ PGLPPKVAAR ANIPPAVVVT
RKATPTAPSV PARNRLSPPL PSGGTTATVH HYPQHHLPGQ RPIPPKNTTG RSSRQAGDES
GVISSASSEP RSTDPTKSTG KRPNQPSQAP QSASATASQV RGRLKTALSN FRRSAPLTES
ISKRATTAEP GAPTNSMTVT PSRPATTTGI PTSDSSSKPP SRCDNASRPR PPLPDTKPNI
ASKLRQPSNI NGPR
//
