ID G7YN70_CLOSI Unreviewed; 287 AA.
AC G7YN70;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Minichromosome maintenance protein 8 {ECO:0000313|EMBL:GAA54401.1};
GN ORFNames=CLF_102746 {ECO:0000313|EMBL:GAA54401.1};
OS Clonorchis sinensis (Chinese liver fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis.
OX NCBI_TaxID=79923 {ECO:0000313|EMBL:GAA54401.1, ECO:0000313|Proteomes:UP000008909};
RN [1] {ECO:0000313|EMBL:GAA54401.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Henan {ECO:0000313|EMBL:GAA54401.1};
RX PubMed=22023798; DOI=10.1186/gb-2011-12-10-r107;
RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., Lv X.,
RA Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., Hu X., Xu J.,
RA Yu X.;
RT "The draft genome of the carcinogenic human liver fluke Clonorchis
RT sinensis.";
RL Genome Biol. 12:R107-R107(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Henan;
RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W.,
RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L.,
RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., Xu J.,
RA Wu Z., Yu X.;
RT "The genome and transcriptome sequence of Clonorchis sinensis provide
RT insights into the carcinogenic liver fluke.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DF143889; GAA54401.1; -; Genomic_DNA.
DR AlphaFoldDB; G7YN70; -.
DR Proteomes; UP000008909; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR CDD; cd22247; MCM8_WHD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11630:SF47; DNA HELICASE MCM8; 1.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008909}.
FT DOMAIN 105..186
FT /note="MCM AAA-lid"
FT /evidence="ECO:0000259|Pfam:PF17855"
SQ SEQUENCE 287 AA; 31658 MW; 54BC9EE59C37FEFD CRC64;
MTTSYIEASR GHMNQLRTTQ RFDLVFVLLD RPDETADRLL SEHVTAVHTG SWKPSSFVCT
PASQPGSDRT PRPHISAVDI DPQAPLAQRL EIRVGERVDY IPSVLLRKYI LYARKYVMPS
LSTAAAMTLR DFYLELRRNR HERDTFPVTV RQLESLVRLT EARARAELRE EATKEDALDV
CQLMRATGLG TGHVGGTPAN ATLSEIAKSI PVSRRATSDS GPAAAKRLLA ALELAARNSN
SRLFTRAEIQ TLVTGLSLSA GSVDPLINRL NDSGALLKQG PTLYKLI
//
