ID G8B953_CANPC Unreviewed; 376 AA.
AC G8B953;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=PWWP domain-containing protein {ECO:0000259|PROSITE:PS50812};
GN OrderedLocusNames=CPAR2_301410 {ECO:0000313|CGD:CAL0000153277,
GN ECO:0000313|EMBL:CCE41152.1};
OS Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia
OS parapsilosis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=578454 {ECO:0000313|EMBL:CCE41152.1, ECO:0000313|Proteomes:UP000005221};
RN [1] {ECO:0000313|Proteomes:UP000005221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
RN [2] {ECO:0000313|Proteomes:UP000005221}
RP GENOME REANNOTATION.
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=22192698; DOI=10.1186/1471-2164-12-628;
RA Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G., Corton N.J.,
RA Berriman M., Butler G.;
RT "Using RNA-seq to determine the transcriptional landscape and the hypoxic
RT response of the pathogenic yeast Candida parapsilosis.";
RL BMC Genomics 12:628-628(2011).
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DR EMBL; HE605204; CCE41152.1; -; Genomic_DNA.
DR AlphaFoldDB; G8B953; -.
DR STRING; 578454.G8B953; -.
DR EnsemblFungi; CPAR2_301410-T; CPAR2_301410-T-p1; CPAR2_301410.
DR CGD; CAL0000153277; CPAR2_301410.
DR VEuPathDB; FungiDB:CPAR2_301410; -.
DR eggNOG; ENOG502S6Q4; Eukaryota.
DR Proteomes; UP000005221; Chromosome 3.
DR Gene3D; 2.30.30.140; -; 1.
DR InterPro; IPR000313; PWWP_dom.
DR PANTHER; PTHR12550; HEPATOMA-DERIVED GROWTH FACTOR-RELATED; 1.
DR PANTHER; PTHR12550:SF49; JIL-1 ANCHORING AND STABILIZING PROTEIN, ISOFORM A; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005221}.
FT DOMAIN 7..76
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 121..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..137
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 376 AA; 42644 MW; 22B1C72FE678E236 CRC64;
MLEEYPPKSI VIAKVKGYPA WPAMVLDPDL LPSHILNKRP KNKQQEPTPN VLPIKFFSDD
TYIWIKSNDI KPLSKDDIAA HFVQSSQKRR KDTVLDQAFR LASDPLDMEV FIKYGSKGAP
DVIEMDEDDD NDENDEEETV VVKTPARKKQ KVSTTSKSTS SKRSIAEAKR EAERELLAQY
DSDWGLQDIN KYSIKEGNYI FDSLAEQKAV FDNIPDISQF SELYEKSIEK FKKIEEQVIE
QLLSATPNTD ELCHLLTQFS ALISKLPRSS ITKSQLLRAL ILDQRKHSSD QAQHEFKDKT
AKILKRLGIE VRENTEDELV VKSENSTAQS TPASTAQSTP EVTEPVRKEE IVVKQESEAV
NSVDSPLKHE VQINGN
//
