ID G8BFT0_CANPC Unreviewed; 1209 AA.
AC G8BFT0;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=K Homology domain-containing protein {ECO:0000259|SMART:SM00322};
GN OrderedLocusNames=CPAR2_203570 {ECO:0000313|CGD:CAL0000156761,
GN ECO:0000313|EMBL:CCE42714.1};
OS Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia
OS parapsilosis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=578454 {ECO:0000313|EMBL:CCE42714.1, ECO:0000313|Proteomes:UP000005221};
RN [1] {ECO:0000313|Proteomes:UP000005221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
RN [2] {ECO:0000313|Proteomes:UP000005221}
RP GENOME REANNOTATION.
RC STRAIN=CDC 317 / ATCC MYA-4646 {ECO:0000313|Proteomes:UP000005221};
RX PubMed=22192698; DOI=10.1186/1471-2164-12-628;
RA Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G., Corton N.J.,
RA Berriman M., Butler G.;
RT "Using RNA-seq to determine the transcriptional landscape and the hypoxic
RT response of the pathogenic yeast Candida parapsilosis.";
RL BMC Genomics 12:628-628(2011).
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DR EMBL; HE605206; CCE42714.1; -; Genomic_DNA.
DR AlphaFoldDB; G8BFT0; -.
DR STRING; 578454.G8BFT0; -.
DR EnsemblFungi; CPAR2_203570-T; CPAR2_203570-T-p1; CPAR2_203570.
DR CGD; CAL0000156761; CPAR2_203570.
DR VEuPathDB; FungiDB:CPAR2_203570; -.
DR eggNOG; KOG2208; Eukaryota.
DR Proteomes; UP000005221; Chromosome 2.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22450; KH-I_ScSCP160_rpt5; 1.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 8.
DR InterPro; IPR004087; KH_dom.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR PANTHER; PTHR10288; KH DOMAIN CONTAINING RNA BINDING PROTEIN; 1.
DR PANTHER; PTHR10288:SF171; P-ELEMENT SOMATIC INHIBITOR, ISOFORM C; 1.
DR Pfam; PF00013; KH_1; 6.
DR SMART; SM00322; KH; 11.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 7.
DR PROSITE; PS50084; KH_TYPE_1; 6.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005221};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00117}.
FT DOMAIN 108..170
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 171..255
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 329..389
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 560..634
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 641..714
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 718..797
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 802..873
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 877..955
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 959..1027
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 1028..1135
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT DOMAIN 1138..1209
FT /note="K Homology"
FT /evidence="ECO:0000259|SMART:SM00322"
FT REGION 1..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 759..782
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 688..715
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1209 AA; 133124 MW; F95A30AEADF4353C CRC64;
MPTPAEIIAA RLNNQSEEVE QEEVEGIVAP EPKSRSNTPS INDDSAFPAL GSKMGSGVQQ
SGATSWGPKM KAPPTAVPVA SNTPKTSKNG NGFAVKPKIS TIQEAFSLDV EDQLNVARPE
FIKILTYVMQ ETKTNVECTT SQHTKKRTFL ISGKPDDVKL AKRLVVKKLT KPVQINFNVP
AKLRSRIIGQ GGRTLKPIIQ ANEVRIEIGD KEESYNSGDA SDDEDDLFAT TVVISIDGDV
EGAKAAKSEI LAIVREETKN LTVKVPLNEN VKPFAEKELQ SIVDQNNELD FSIPTFKSGS
NSIVIHGERE LALEARANVK AALEKLSQKI VTEEVPIPRT KYQFLPIDEV LSKCNVLIQL
PKDGETNVKF IGEKKNIKLA QEEARKVTSQ YKVEILDMSK AHKGNLRHVS AVAAYLNKIG
AFKTIAEAND VVINAPKIKE LNDESVTSIP IQIVSKGGDE QIKAAKKSIV SQVNKITPDQ
TKVIDDIESF LLNRVDGVIG ALAQKEKVEY VILQNVIVLF NSQNQQEEEA EDFDDIDSSG
DDAFAKINSA LNTLRELAAN LSSATLEVPT KDQKEVVSGP KGVTLRSILS TVEPDTVSVK
LHSNGTSLSE NEIYIHGIKS SVATIKKEIE SVLADAKEYP DGFTSEVRVP SQILSRLVGK
NGSFLNTLRD EFGVRIDVPE QDAKKDDSEK AEVTIKGVKK NVEAARAKIS ALAKKWADET
LVRVRIENQY HRRMIGAQGV FINRLQDKYN VKIRFPAADA SSPSPFADAP KSKDEVTIKG
PSKGVAKAEE ELQELYQFEK ENGFKKLLQI PSKAVARIIG KNGETIKDIA DGTGVEYNFK
RENDESSGFV ELELTGSKAA LKDATTKIQE IIDEVENFVV RTIKVDTKYH RDLVGPSGSV
MKQIISSAGG DDLPRGKYHR LLTIPNEGSG SDEVVSQGDK TIVDKIISAI EKIVEEKEAS
IVEEIDLPKE KHRLIIGPSG SIRHSLQSDF GVTIEIPRAN DESTIVKVSG LPEKVAAAKD
KIEELTKDDW KVSIDILEKY HPLVSEHGAI FKKLKSDYKV EVTHGDFTRR ASKLSSALIP
APVESAYPEN EEEFKFTIEE LVPENSDDDV VIPWRLKGDE EDVEKAVQLI NKKLELAKSA
TAHAWFYASK PSVFSKIIGP QGSKVNKLRS KTNTFITIPR ANDKFSKFIY LVGDEINLNE
AHEEIKKLL
//
