ID G8BW27_TETPH Unreviewed; 553 AA.
AC G8BW27;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0000259|SMART:SM01340};
GN Name=TPHA0G02680 {ECO:0000313|EMBL:CCE64105.1};
GN OrderedLocusNames=TPHA_0G02680 {ECO:0000313|EMBL:CCE64105.1};
OS Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL
OS Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Tetrapisispora.
OX NCBI_TaxID=1071381 {ECO:0000313|EMBL:CCE64105.1, ECO:0000313|Proteomes:UP000005666};
RN [1] {ECO:0000313|EMBL:CCE64105.1, ECO:0000313|Proteomes:UP000005666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5
RC {ECO:0000313|Proteomes:UP000005666};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
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DR EMBL; HE612862; CCE64105.1; -; Genomic_DNA.
DR RefSeq; XP_003686539.1; XM_003686491.1.
DR AlphaFoldDB; G8BW27; -.
DR STRING; 1071381.G8BW27; -.
DR GeneID; 11535888; -.
DR KEGG; tpf:TPHA_0G02680; -.
DR eggNOG; KOG1978; Eukaryota.
DR HOGENOM; CLU_024335_0_0_1; -.
DR OrthoDB; 1369806at2759; -.
DR Proteomes; UP000005666; Chromosome 7.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF44; DNA MISMATCH REPAIR PROTEIN MLH2; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Reference proteome {ECO:0000313|Proteomes:UP000005666}.
FT DOMAIN 242..358
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
SQ SEQUENCE 553 AA; 62964 MW; C0D1B278157716A2 CRC64;
MAIKEICIND RLTLHSSAYL IDPAATVREL IDNSVDSGSS NIVVELDSKT GGCEYISVKD
NGSGVMPNDR PLMCLNHYTS KTKAFSDLQS IDTLGFRGNA LSIIANLASQ KGSVQITTRT
NLEEIGETWF VDKLGSIKDN KIKKVNSEVG TKVVIKKLLK GLYVRNIECS KKGRSTIEKV
KNLLTHYSLN FKSIKFQFFL IKLNKDQSIA LRHMQRNTEL NLSRVRNLMI LAGLPPTAKN
MILNESGIKI NENFQIDLIL PGYLFQHGND TSKKNCKFLT VNNRALSLSL SFGKEITKIL
NYSYQALDLV KPKFWFLCFH INPSMIDINI EPEKNDIFIK NQSAIFDSFS SLVTDFLLRS
KLHNLDSPPK EIYINEKHGS QEPGEVQHTV NCNKTSSAEL LLSRGNERKE YKDYAFSLNR
YQIPKKHIRK KKLTSEQIIL SLQNTPNEKS LGTSLLKDYS MKNRNFYHSQ MRKIGLYSEY
TNKISINVTV STALTNSYNY KNDLNWLMRD SSLNIALSSK MIELEQELHG NITGIINKTS
HGWYYYTTKK DDN
//
