ID   G8E3T5_SESIN            Unreviewed;       176 AA.
AC   G8E3T5;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=NBS-LRR class disease resistance protein {ECO:0000313|EMBL:AEQ61806.1};
DE   Flags: Fragment;
OS   Sesamum indicum (Oriental sesame) (Sesamum orientale).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Lamiales; Pedaliaceae; Sesamum.
OX   NCBI_TaxID=4182 {ECO:0000313|EMBL:AEQ61806.1};
RN   [1] {ECO:0000313|EMBL:AEQ61806.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=SIRGA24 {ECO:0000313|EMBL:AEQ61806.1};
RA   Gao S.G., Liu H.Y., Ni Y.X., Wang J.M.;
RT   "The clone of resistance gene analogs from Sesamum indicum.";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Confers resistance to late blight (Phytophthora infestans)
CC       races carrying the avirulence gene Avr1. Resistance proteins guard the
CC       plant against pathogens that contain an appropriate avirulence protein
CC       via an indirect interaction with this avirulence protein. That triggers
CC       a defense system including the hypersensitive response, which restricts
CC       the pathogen growth. {ECO:0000256|ARBA:ARBA00002074}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
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DR   EMBL; JF708100; AEQ61806.1; -; Genomic_DNA.
DR   AlphaFoldDB; G8E3T5; -.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:InterPro.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR23155; DISEASE RESISTANCE PROTEIN RP; 1.
DR   PANTHER; PTHR23155:SF1235; DISEASE RESISTANCE RPP13-LIKE PROTEIN 1; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Hypersensitive response {ECO:0000256|ARBA:ARBA00022667};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Plant defense {ECO:0000256|ARBA:ARBA00022667}.
FT   DOMAIN          1..176
FT                   /note="NB-ARC"
FT                   /evidence="ECO:0000259|Pfam:PF00931"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AEQ61806.1"
FT   NON_TER         176
FT                   /evidence="ECO:0000313|EMBL:AEQ61806.1"
SQ   SEQUENCE   176 AA;  20164 MW;  512CC4694A975DF8 CRC64;
     GMGGFGKTTL ARNLYKDRLV SVHFDVRAWA TISQDYDVGK ILLGLLRLVI RRPTYEMLQM
     GNEELGEHLR TTLMGRRYLI ILDDIWNTHS WNDITKFFPD NNNGSRIIIT TRNSSLANFI
     AFRSPHHNMY LLKDDESWNL IHQKVFAPGE ICSPGLESIG RKIAHNCRGL PLALKV
//