ID G8E7W4_9HYPO Unreviewed; 530 AA.
AC G8E7W4;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 08-NOV-2023, entry version 31.
DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418};
DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418};
DE Flags: Fragment;
OS Fusarium sp. NRRL 22110.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=1101235 {ECO:0000313|EMBL:AER40884.1};
RN [1] {ECO:0000313|EMBL:AER40884.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRRL 22110 {ECO:0000313|EMBL:AER40884.1};
RX PubMed=22086911; DOI=10.3852/11-179;
RA O'Donnell K., Humber R.A., Geiser D.M., Kang S., Park B., Robert V.A.,
RA Crous P.W., Johnston P.R., Aoki T., Rooney A.P., Rehner S.A.;
RT "Phylogenetic diversity of insecticolous fusaria inferred from multilocus
RT DNA sequence data and their molecular identification via FUSARIUM-ID and
RT Fusarium MLST.";
RL Mycologia 104:427-445(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JF740948; AER40884.1; -; Genomic_DNA.
DR AlphaFoldDB; G8E7W4; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR007075; RNA_pol_Rpb1_6.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000313|EMBL:AER40884.1};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 2..127
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04983"
FT DOMAIN 154..258
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF05000"
FT DOMAIN 265..530
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04998"
FT DOMAIN 331..515
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04992"
FT REGION 187..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AER40884.1"
FT NON_TER 530
FT /evidence="ECO:0000313|EMBL:AER40884.1"
SQ SEQUENCE 530 AA; 58573 MW; D95233FAAB1E6462 CRC64;
QQVMNVMLWV PGWDGIIPQP AILKPRPRWT GKQIISMVIP PEVSLLDIKE GSKDYSPLKD
DGLLIQNGQL MYGLLTKKNV GASAGGIIHV CYNELGPEGA MAFLNGVQQT VTYWLLNTGH
SIGIGDTIPD KATIEKIQAH IDASKNTVAD LTAKATSNEL EALPGMNVRD TFENKVSMAL
NAARDKAGTS TQQSLKDSNN AVTMASSGSK GSSINISQMT ALVGQQSVEG KRIPFGFKYR
TLPHFTKDDY SPEARGFVEN SYLRGLTPSE FFFHAMAGRE GLIDTAVKTA ETGYIQRRLV
KALEDLSARY DGTIRNSLGD IVQFLYGEDG LDAMCIEKQK FGTLNMSHAA FEQKYRLDLA
NPPEWFRKDY EYGNELTGDK PSMALLDEEW EQLQIDRRAV RKINAIKGND EMMQLPLNTG
RIVEGAKRIF NIKATDRSNL RPSDVIPAVQ ALLDKVKIVQ GTDPISLEAD ANATILFKAL
LRSRLAFKEV VKVHRLNKLA FNHILGELQN KWERAFVSPG EMVGVLAAQS
//
