ID G8E7W8_9HYPO Unreviewed; 528 AA.
AC G8E7W8;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012418};
DE EC=2.7.7.6 {ECO:0000256|ARBA:ARBA00012418};
DE Flags: Fragment;
OS Fusarium sp. NRRL 22289.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=1101240 {ECO:0000313|EMBL:AER40888.1};
RN [1] {ECO:0000313|EMBL:AER40888.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NRRL 22289 {ECO:0000313|EMBL:AER40888.1};
RX PubMed=22086911; DOI=10.3852/11-179;
RA O'Donnell K., Humber R.A., Geiser D.M., Kang S., Park B., Robert V.A.,
RA Crous P.W., Johnston P.R., Aoki T., Rooney A.P., Rehner S.A.;
RT "Phylogenetic diversity of insecticolous fusaria inferred from multilocus
RT DNA sequence data and their molecular identification via FUSARIUM-ID and
RT Fusarium MLST.";
RL Mycologia 104:427-445(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|ARBA:ARBA00024550};
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DR EMBL; JF740952; AER40888.1; -; Genomic_DNA.
DR AlphaFoldDB; G8E7W8; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.132.30; -; 1.
DR Gene3D; 6.10.250.2940; -; 1.
DR Gene3D; 6.20.50.80; -; 1.
DR Gene3D; 1.10.274.100; RNA polymerase Rpb1, domain 3; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007066; RNA_pol_Rpb1_3.
DR InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR InterPro; IPR007083; RNA_pol_Rpb1_4.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR007075; RNA_pol_Rpb1_6.
DR InterPro; IPR038120; Rpb1_funnel_sf.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF37; DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1; 1.
DR Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR Pfam; PF04992; RNA_pol_Rpb1_6; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000313|EMBL:AER40888.1};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 2..123
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04983"
FT DOMAIN 151..254
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF05000"
FT DOMAIN 261..528
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04998"
FT DOMAIN 327..511
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04992"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AER40888.1"
FT NON_TER 528
FT /evidence="ECO:0000313|EMBL:AER40888.1"
SQ SEQUENCE 528 AA; 58721 MW; A9EAC5C6B076BAE6 CRC64;
QQVMNVMLWV PGWDGIIPQP AILKPRPRWT GKQIISMVIP PEVSLKDGKD NSPLKDEGIL
IQNGQLMYGL LTKKNVGASA GGIIHICYNE LGPEGAMAFL NGVQQTVTYW LLNTGHSIGI
GDTIPDKATI EKIQAHIDAE KSEVARLTAM ATSNELEALP GMNVRDTFEN KVSMALNAAR
DKAGTTTQKS LKDSNNAVTM ASSGSKGSSI NISQMTALVG QQSVEGKRIP FGFKYRTLPH
FTKDDYSPEA RGFVENSYLR GLTPSEFFFH AMAGREGLID TAVKTAETGY IQRRLVKALE
DLSARYDGTI RNSLGDIVQF LYGEDGLDAM CIEKQRFGTL NMSHAEFEKK YRLDLANPPE
WFRKEYEYGN ELTGDKPSMA LLDEEWEQLQ TDRQVVRRIN QIKGNEEMMQ LPLNTGRIME
GAKRIFNIKA TDRSNLRPSD VIPAVQALLD KVKIVQGRDP ISIEADENAT MLFKALLRSR
LAFKEIVMVH RLNKLAFNHI LGELQSKWER AFVSPGEMVG VLAAQSIG
//
