ID   G8F2G7_MACFA            Unreviewed;       525 AA.
AC   G8F2G7;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   22-FEB-2023, entry version 23.
DE   RecName: Full=G-patch domain-containing protein {ECO:0000259|PROSITE:PS50174};
GN   ORFNames=EGM_20826 {ECO:0000313|EMBL:EHH61481.1};
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541 {ECO:0000313|Proteomes:UP000009130};
RN   [1] {ECO:0000313|EMBL:EHH61481.1, ECO:0000313|Proteomes:UP000009130}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CE-4 {ECO:0000313|EMBL:EHH61481.1,
RC   ECO:0000313|Proteomes:UP000009130};
RX   PubMed=22002653; DOI=10.1038/nbt.1992;
RA   Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., Li Q.,
RA   Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., Huang Z.,
RA   Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., Huang Y.,
RA   Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., Li B., Liu X.,
RA   Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., Li Y., Wang W.,
RA   Katze M.G., Su B., Nielsen R., Yang H., Wang J., Wang X., Wang J.;
RT   "Genome sequencing and comparison of two nonhuman primate animal models,
RT   the cynomolgus and Chinese rhesus macaques.";
RL   Nat. Biotechnol. 29:1019-1023(2011).
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DR   EMBL; JH330031; EHH61481.1; -; Genomic_DNA.
DR   AlphaFoldDB; G8F2G7; -.
DR   eggNOG; ENOG502QQ66; Eukaryota.
DR   OrthoDB; 3060636at2759; -.
DR   Proteomes; UP000009130; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0039536; P:negative regulation of RIG-I signaling pathway; IEA:InterPro.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; IEA:InterPro.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR040341; GPATCH3.
DR   PANTHER; PTHR14390; G PATCH DOMAIN CONTAINING PROTEIN 3; 1.
DR   PANTHER; PTHR14390:SF2; G PATCH DOMAIN-CONTAINING PROTEIN 3; 1.
DR   Pfam; PF01585; G-patch; 1.
DR   SMART; SM00443; G_patch; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
PE   4: Predicted;
FT   DOMAIN          410..458
FT                   /note="G-patch"
FT                   /evidence="ECO:0000259|PROSITE:PS50174"
FT   REGION          262..316
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        279..294
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        295..316
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   525 AA;  59051 MW;  8F2EF88D1EA88E86 CRC64;
     MAVPGEAEEE ATVYLVVSGI PSVLRSAHLR SYFSQFREER GGGFLCFHYR HRPERAPPQA
     APNSALTPTG PAAGGQLLAQ TSATDVRPLS TRDSAPIQTR TCCCVISVRG LAQAQRLLRM
     YSGRRWLDSH GTWLPGRCLI RRLRLPTEAS GLGSFSFKTR KEMQSRKAEN EAFTLADLKQ
     LPELNPPVLM PNGNVGTPLR VFLELIRACR LPPRIITQLQ LQFPKTGSSR RYGNVPFEYE
     DAETVEQEEL VYTAEGEEIP QGTCLADIPA SPCGEPEEEA RKEEEEESHS DDDDDRGEEW
     ERHEALHEDV TGQERTTEQL FEEEIELKWE KGGSGLVFYT DAQFWQEEEG DFDEQTADDW
     DVDMSVYYDR DGGDKDARDS VQMRLEQRLR DGQEDGSVIE RQVGTFERHT KGIGRKVMER
     QGWAEGQGLG SRCSGVPEAL DSDGQHPRCK RGLGYHGEKL QPFGQLKRPR RNGLGLISTI
     YDEPLPQDQT ESLLRRQPPT SMKFRTDMAF VRGSSCASDS PSLPD
//