ID   G8J9G8_CYPCA            Unreviewed;        73 AA.
AC   G8J9G8;
DT   25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT   25-JAN-2012, sequence version 1.
DT   22-FEB-2023, entry version 33.
DE   SubName: Full=Toll-like receptor 4 {ECO:0000313|EMBL:AET24925.1};
DE   Flags: Fragment;
GN   Name=TLR4 {ECO:0000313|EMBL:AET24925.1};
OS   Cyprinus carpio (Common carp).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Cyprininae; Cyprinus.
OX   NCBI_TaxID=7962 {ECO:0000313|EMBL:AET24925.1};
RN   [1] {ECO:0000313|EMBL:AET24925.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Uma A., Rebecca G., Saravanabava K.;
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; JN867636; AET24925.1; -; mRNA.
DR   AlphaFoldDB; G8J9G8; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR017241; Toll-like_receptor.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR24365; TOLL-LIKE RECEPTOR; 1.
DR   PANTHER; PTHR24365:SF521; TOLL-LIKE RECEPTOR 4; 1.
DR   Pfam; PF01582; TIR; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   2: Evidence at transcript level;
KW   Receptor {ECO:0000313|EMBL:AET24925.1}.
FT   DOMAIN          16..73
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AET24925.1"
FT   NON_TER         73
FT                   /evidence="ECO:0000313|EMBL:AET24925.1"
SQ   SEQUENCE   73 AA;  8247 MW;  23C87303F67A1045 CRC64;
     CCILLRGYRS PGQQECSYDA FVIFSSYDEV WVMNELMENL ENGVPPIQLC LHMRDFQAGK
     SIASNIIDEG IMG
//