ID G8JTG9_ERECY Unreviewed; 565 AA.
AC G8JTG9;
DT 25-JAN-2012, integrated into UniProtKB/TrEMBL.
DT 25-JAN-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Choline kinase N-terminal domain-containing protein {ECO:0000259|Pfam:PF04428};
GN OrderedLocusNames=Ecym_4258 {ECO:0000313|EMBL:AET39322.1};
OS Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 /
OS NRRL Y-17582) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=931890 {ECO:0000313|EMBL:AET39322.1, ECO:0000313|Proteomes:UP000006790};
RN [1] {ECO:0000313|Proteomes:UP000006790}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582
RC {ECO:0000313|Proteomes:UP000006790};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
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DR EMBL; CP002500; AET39322.1; -; Genomic_DNA.
DR RefSeq; XP_003646139.1; XM_003646091.1.
DR AlphaFoldDB; G8JTG9; -.
DR STRING; 931890.G8JTG9; -.
DR GeneID; 11471288; -.
DR KEGG; erc:Ecym_4258; -.
DR eggNOG; KOG2686; Eukaryota.
DR HOGENOM; CLU_012712_4_2_1; -.
DR InParanoid; G8JTG9; -.
DR OMA; CEQVINW; -.
DR OrthoDB; 144299at2759; -.
DR Proteomes; UP000006790; Chromosome 4.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR CDD; cd05157; ETNK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR007521; Choline_kin_N.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF93; RE24176P; 1.
DR Pfam; PF04428; Choline_kin_N; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006790}.
FT DOMAIN 78..114
FT /note="Choline kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04428"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 565 AA; 64310 MW; B630DE60B00B8BC9 CRC64;
MVKADPRSSK SESQLAGKGS WSRSNSRTRK PLLPRTKSSQ RLIRTISVEQ KSEDASNALA
DELSSSLLQL SLGSDSHEFI EVPFVKATLD ITLPMDYLKV DVLHMIQSLK IPKWCKASGK
PLVTNPNELT LTMITGTMTN AIYKVERNKH TRLPSLLLRV YGPNVESIID RAYELETLAR
LSFQNIGPSL FGCFNNGRFE QFLENSKTLT KDDIRDWKTA QRIARRMKEF HGGVPLLEWE
KKHCIAWSRI DKWVSKMDSS EWIQNIDHLK GALLTSDWTH FKNIINKYRL WLDATGESSK
PLVFCHNDTQ YGNLLFTSPV ITPTTSTPLA ASSSATSLSD SLFLTESNIS LEDIINPSVE
DQKQDSKLVV IDFEYAGPNP AAYDLANFLS EWMSDYHCTD CYKTFEDKFP KREEILNFVY
SYTSHLRNKQ PPVEEEVRNL YNSIIRWRPC VSLHWSLWGL IQSGKLDSKP QTSTVVEEEG
PGGEKYIITL EDKEPYDSDD LTYDEDVNPN NLKEATGADI HSFDYISYAK EKISVFYGDL
VQLGVIEEAD LPESTPLKKL DVKFL
//
