ID G8N1S2_GEOTH Unreviewed; 368 AA.
AC G8N1S2;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Histidine kinase dimerization and phosphoacceptor region {ECO:0000313|EMBL:AEV17544.1};
GN ORFNames=GTCCBUS3UF5_2170 {ECO:0000313|EMBL:AEV17544.1};
OS Geobacillus thermoleovorans CCB_US3_UF5.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC Geobacillus thermoleovorans group.
OX NCBI_TaxID=1111068 {ECO:0000313|EMBL:AEV17544.1, ECO:0000313|Proteomes:UP000005636};
RN [1] {ECO:0000313|EMBL:AEV17544.1, ECO:0000313|Proteomes:UP000005636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCB_US3_UF5 {ECO:0000313|EMBL:AEV17544.1,
RC ECO:0000313|Proteomes:UP000005636};
RA Muhd Sakaff M.K.L., Abdul Rahman A.Y., Saito J.A., Hou S., Alam M.;
RT "Complete genome sequence of thermophilic Geobacillus thermoleovorans
RT CCB_US3_UF5.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003125; AEV17544.1; -; Genomic_DNA.
DR RefSeq; WP_014194660.1; NC_016593.1.
DR AlphaFoldDB; G8N1S2; -.
DR KEGG; gte:GTCCBUS3UF5_2170; -.
DR PATRIC; fig|1111068.3.peg.205; -.
DR HOGENOM; CLU_000445_20_3_9; -.
DR Proteomes; UP000005636; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF64; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AEV17544.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 29..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 57..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 177..242
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT COILED 131..165
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 368 AA; 41476 MW; 1140A1364F757D27 CRC64;
MESLLIIYKL IVWGYAAFDY ISSKQRTGAG FVLVSLIYFC LQLFALIVRH MSWKRGAAFG
SVALLVLAAA FVEPLWALLL PLNGYELASV YIHRVWGIGA VLLTPMIWLD PSAGKLYGFV
ALFSFVSVTA VKRHIERMEQ QEDRLDQMRN DLHRLTRRIS EYHQYIKQSE YTLQLEERNR
LSQRIHDQIG HSLAGALIQM EAAKRLMDGD RDKAKQLLEN AIHISKEGME QIRMTLKQIK
PPLEQIGLNR VKLFIEEFSA QHHLPVPLVC KGDLDVITPI QWKVIYENIA EALTNASKYA
EATAIAVEIH VLNRVIKVEV KDNGKGAAKI KKGLGIIGME ERAASVHGTV IVDGTNGFSV
TTLLPIHE
//
