ID G8N1Z3_GEOTH Unreviewed; 751 AA.
AC G8N1Z3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE SubName: Full=DNA segregation ATPase FtsK/SpoIIIE {ECO:0000313|EMBL:AEV18788.1};
GN ORFNames=GTCCBUS3UF5_14750 {ECO:0000313|EMBL:AEV18788.1};
OS Geobacillus thermoleovorans CCB_US3_UF5.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC Geobacillus thermoleovorans group.
OX NCBI_TaxID=1111068 {ECO:0000313|EMBL:AEV18788.1, ECO:0000313|Proteomes:UP000005636};
RN [1] {ECO:0000313|EMBL:AEV18788.1, ECO:0000313|Proteomes:UP000005636}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCB_US3_UF5 {ECO:0000313|EMBL:AEV18788.1,
RC ECO:0000313|Proteomes:UP000005636};
RA Muhd Sakaff M.K.L., Abdul Rahman A.Y., Saito J.A., Hou S., Alam M.;
RT "Complete genome sequence of thermophilic Geobacillus thermoleovorans
RT CCB_US3_UF5.";
RL Submitted (NOV-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003125; AEV18788.1; -; Genomic_DNA.
DR AlphaFoldDB; G8N1Z3; -.
DR KEGG; gte:GTCCBUS3UF5_14750; -.
DR PATRIC; fig|1111068.3.peg.1428; -.
DR HOGENOM; CLU_001981_9_6_9; -.
DR Proteomes; UP000005636; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 30..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 415..611
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 192..231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 244..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..217
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..262
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 432..439
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 751 AA; 82499 MW; F64AA387966617C6 CRC64;
MIGLGLLAVA VVAMARLGLV GETLVLVGRF FFGEWYMLLV GGLFLLSLIV MWRREWPSWT
GRPFVGASSI AAALLLLSHD KLFELMSRRG ELDPSIIRTT WGLFWNEASG KAADVDLGGG
MVGALLFAAS YQLFDSPGTK WICFLLFIVG FVVLTGKSLR ETAGKWVAFA AAFVRKEWLA
FVEDIKQWRA GRKRKESGGR SRRSRRAAAK REDEPAEASS VEPDEELLSP PPIISDFAAV
RSAAEPEEEK NPLVEGDSGG EEDKPAPPLA FSEHENTNYD LPPLDLLRLP KPAGQSADHA
NIYANARKLE KTFQSFGVKA KVTQVHLGPA VTKYEVYPDV GVKVSKIVSL SDDLALALAA
KDIRIEAPIP GKSAIGIEVP NEEIATVSLR EVLEAIEHTR DKAKLLIPLG RDISGEVVAA
ELNKMPHLLI AGATGSGKSV CINGIIVSLL MRTKPHEVKL MMIDPKMVEL SVYNGVPHLL
TPVVTDAKKA AQALKKVVQE MERRYELFSH TGTRNIEGYN EHIRHHNETA SEQQPLLPYI
VVIIDELADL MMVASSDVEE AITRLAQMAR AAGIHLIIAT QRPSVDVITG VIKANIPSRI
AFSVSSQIDS RTILDMGGAE KLLGRGDMLF LPMGASKPVR VQGAFVSDQE VEEVVRFVIG
QQQAQYYEEM FVEDSEPSSS ALEDELYDEA VRLVVEMQSA SVSMLQRRFR IGYNRAARLI
DAMEERGVVG PYEGSKPRAV LWSKEDLKKT S
//
