ID G8R1V2_OWEHD Unreviewed; 427 AA.
AC G8R1V2;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:AEV32878.1};
GN OrderedLocusNames=Oweho_1899 {ECO:0000313|EMBL:AEV32878.1};
OS Owenweeksia hongkongensis (strain DSM 17368 / CIP 108786 / JCM 12287 / NRRL
OS B-23963 / UST20020801).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Owenweeksiaceae;
OC Owenweeksia.
OX NCBI_TaxID=926562 {ECO:0000313|EMBL:AEV32878.1, ECO:0000313|Proteomes:UP000005631};
RN [1] {ECO:0000313|EMBL:AEV32878.1, ECO:0000313|Proteomes:UP000005631}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 17368 / JCM 12287 / NRRL B-23963
RC {ECO:0000313|Proteomes:UP000005631};
RX PubMed=23450211; DOI=10.4056/sigs.3296896;
RA Riedel T., Held B., Nolan M., Lucas S., Lapidus A., Tice H., Del Rio T.G.,
RA Cheng J.F., Han C., Tapia R., Goodwin L.A., Pitluck S., Liolios K.,
RA Mavromatis K., Pagani I., Ivanova N., Mikhailova N., Pati A., Chen A.,
RA Palaniappan K., Rohde M., Tindall B.J., Detter J.C., Goker M., Woyke T.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P.,
RA Kyrpides N.C.;
RT "Genome sequence of the orange-pigmented seawater bacterium Owenweeksia
RT hongkongensis type strain (UST20020801(T)).";
RL Stand. Genomic Sci. 7:120-130(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP003156; AEV32878.1; -; Genomic_DNA.
DR RefSeq; WP_014202234.1; NC_016599.1.
DR AlphaFoldDB; G8R1V2; -.
DR STRING; 926562.Oweho_1899; -.
DR KEGG; oho:Oweho_1899; -.
DR PATRIC; fig|926562.3.peg.1905; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_14_1_10; -.
DR OrthoDB; 9809068at2; -.
DR Proteomes; UP000005631; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF33; EFFLUX PROTEIN; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005631}.
FT DOMAIN 47..268
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 408..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..427
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 427 AA; 46607 MW; 240314A86A7759DD CRC64;
MSKRLRYGLI IGAVILVIAL VVAKKKGAIG SSDATEVTIG KVEKLTLEET VIASGKIQPE
VEVKLSPEVS GEIIELPIEE GQDVKKGDLV VRINPDIYQS AVNRAKAALN SSKAALASSK
AQQVEAKNIF DRNDKLYKQK VISDAEYDAA KRGYDVANLN VESAQFQQQS AEATYREALD
NLQRTTIYAP QDGTVSMLNV EIGERVVGTA QMAGTEIARI ANLENMEVLV EVNENDIIRV
SMGDTAIVEV DAYLDKEFVG VVTEIANSAQ LTGVSADQVT NFEVKVRVLK ESYEGMLKEG
EKSPFRPGMT ASVEIKTEKK KDVIAVPIES VTTRSDTSTK AKSYKIGRED TESKEDYEVV
FLYADGKAKL QVVSTGIQDD ENIEVLSGLE DGQQVITGPY SLVSKQLVNG DKVEEKDSKK
EEKSKDK
//
