ID G8R3K1_OWEHD Unreviewed; 3474 AA.
AC G8R3K1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=RHS repeat-associated core domain protein {ECO:0000313|EMBL:AEV33057.1};
GN OrderedLocusNames=Oweho_2082 {ECO:0000313|EMBL:AEV33057.1};
OS Owenweeksia hongkongensis (strain DSM 17368 / CIP 108786 / JCM 12287 / NRRL
OS B-23963 / UST20020801).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Owenweeksiaceae;
OC Owenweeksia.
OX NCBI_TaxID=926562 {ECO:0000313|EMBL:AEV33057.1, ECO:0000313|Proteomes:UP000005631};
RN [1] {ECO:0000313|EMBL:AEV33057.1, ECO:0000313|Proteomes:UP000005631}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 17368 / JCM 12287 / NRRL B-23963
RC {ECO:0000313|Proteomes:UP000005631};
RX PubMed=23450211; DOI=10.4056/sigs.3296896;
RA Riedel T., Held B., Nolan M., Lucas S., Lapidus A., Tice H., Del Rio T.G.,
RA Cheng J.F., Han C., Tapia R., Goodwin L.A., Pitluck S., Liolios K.,
RA Mavromatis K., Pagani I., Ivanova N., Mikhailova N., Pati A., Chen A.,
RA Palaniappan K., Rohde M., Tindall B.J., Detter J.C., Goker M., Woyke T.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Klenk H.P.,
RA Kyrpides N.C.;
RT "Genome sequence of the orange-pigmented seawater bacterium Owenweeksia
RT hongkongensis type strain (UST20020801(T)).";
RL Stand. Genomic Sci. 7:120-130(2012).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; CP003156; AEV33057.1; -; Genomic_DNA.
DR RefSeq; WP_014202406.1; NC_016599.1.
DR STRING; 926562.Oweho_2082; -.
DR KEGG; oho:Oweho_2082; -.
DR PATRIC; fig|926562.3.peg.2094; -.
DR eggNOG; COG3209; Bacteria.
DR HOGENOM; CLU_000302_0_0_10; -.
DR OrthoDB; 9765204at2; -.
DR Proteomes; UP000005631; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR Gene3D; 2.180.10.10; RHS repeat-associated core; 3.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR022385; Rhs_assc_core.
DR InterPro; IPR031325; RHS_repeat.
DR InterPro; IPR003284; Sal_SpvB.
DR InterPro; IPR022045; TcdB_toxin_mid/N.
DR InterPro; IPR006530; YD.
DR NCBIfam; TIGR03696; Rhs_assc_core; 1.
DR NCBIfam; TIGR01643; YD_repeat_2x; 2.
DR PANTHER; PTHR32305; -; 1.
DR PANTHER; PTHR32305:SF15; PROTEIN RHSA-RELATED; 1.
DR Pfam; PF05593; RHS_repeat; 1.
DR Pfam; PF03534; SpvB; 1.
DR Pfam; PF12256; TcdB_toxin_midN; 1.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005631};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT DOMAIN 1762..1906
FT /note="Insecticide toxin TcdB middle/N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12256"
FT REGION 57..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..71
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3474 AA; 384109 MW; 13F92DD5BB90729A CRC64;
MKNQIDFTTK VAAFVMIATM LGNDLIASTR AMLNFNPAAI NYIEVDSFSS SVPIVEEHSE
NREEEVSSAK DEETSPSNNT AWEARLKTTS IAYLGYHHQD PLHMPEDDFF EFTVPEDFKT
YKNVILEYDI QGLEDGHNIP KSVNGRPVYY GSSIEPGTDW QRVSVELNEA ELKPGNNTIR
FGMPEGFGSS VTVKNVDLLF TNDESTAPLN DRMGRIEASE ADFTIEERLD EDRLFELLSM
DMPSIPNDIK NVTQGADGFL LESFKKDSAR ITIAYQSDVV PSGSGMSRLH LFYFDDERRT
WKVASNLNFD PIAGTVTGQA PSNTDYFAGL ISSPEMPEAS AFVPTAISDI KAANPAAGIS
MINPPSASRT GEASVSYPID IPAGRAGLTP SLMLNYSSDG GAGWLGIGWS INVPQVAVET
SWGVPTFGTG ETEGYLLNGS ALYMEGGLRP NKTAMSSSRA SGDVQFIERT INSYKTITRK
GSAPNNYYWV EKHADGTEYF YGTTDGTSFD ASYVLSDGPG GNIVKWFLAM TKDRWGNYIK
YYYDIGTENS ATDAKKDGHY AVLSKIAYTG FDGGDAPRYI VEFKKTKDRQ DATINLKAGI
KELDYHSLNN IKIRYVDPNL SNDTVEISRY HMTYGNGDFG KKTLLSITKY DKNDDEFHEH
SFTYHTSGNR ITYGNPTPIN TNIGPFNNLF SGMDDKIKKI ALPLSQQAEP SSINSSVTSG
WGAGGSVGLG VCFTGSSFIP TKAWTFSGSM GLSQSVTQSK INLDDFNGDG LPDIMFDAGI
HKAYLPLKTQ ADGSQFFGKS RRISQPGSLN ESMSISFSTG VNFAMPLNAL YYGLNYNNNR
SFNYRYLTDY NADGFKDLVN QGVVYFGRMN QAGDYSFDVS SEQTPNPVIK GTSASTYTDD
ESLPDLQMVR TWEAPMDGYV NISGTATCDV NTVDGLRLGI QKGSTFLVAM TDVSGSSSLN
MVANNVHVNR GEKILFRTQS KNNGYSDLAY WNPKVKYTNN LSRVDPNGID YAESTYEDGF
MLSASQGVIT TDDKYIKVSW PALNSSVNLT DDVTFRISAL WTPNGGTSSS VFSFSNKISA
GSPLNLTGNF VDNNGNPANF VNSFLKIPGY GTGGEWNVFF QVLSSSNVDW KAINWRPEVS
FGDDPCGLPT RKKYPSVMYH TYNKVLQLEA SYPVTTSGAG SDQMRFWPVV SFSNVLSAFT
TDEISEGSPK YAWFVSKTAG GLLSKMVLKI NTNGTYAYYT DKSYSQVVTQ ASSSTVYGFS
REQVLEGTAH VGWFCQDKLL GAFLRSSTSS ISYKNLTQGG IQEATSVNFD VFAINRTALQ
DYHLGWGQFC WNDADNPDAP IGVSEMQLNS SMISEEKNYQ KNEPEISDMQ QEITESSPTP
ATDKFHMLIA RRWERPSRLP SYIKENYANG SDEKLDCWSA WNGHEGVYAN DGATSPGKFA
ESPRMIKPTV PANSGNYLAE GIPIVTTSNS LADNVTAAAG LLGQSETRNI GSAFNSKPQT
AYLDINGDGY PDIIKYDNSD PKMQVTVPLG GYANETDFFD SDGNLGKSIS ESVTMTIAGS
FANNDKRFMK TGNVSGSAGL GSNYSEFEWL DINGDGLPDR VSSDNSTDIL IEYNRGNGLF
EAVSVNTSLS QSSLNKSNST SGSLGLGLSS LDDATDKVGG SFSAGIGLNV TGGEVAKQFI
DYNGDGLLDI AVSSGSAVSV YYNLGTEWSG PFGISGIDLG KSEALGVYGN IAGTYSFPSA
TVPPGASIKT SLSGNAQANF ALNKTNSTLR DMNGDNIPDI VSSDGFGKLS VRYATNVIGN
SNLLSTVTNP LGGSFSINYH REGNKYGNYP VAIKTSTSAD NEVMVWDMPY SKWVLSQVVI
DDGLDLQDQG EDIDGADDIQ LSFKYDGGIK SRRERDFIGF TRVQTLREAD NPMPTVNTDP
IARYTSTVVE YFRPSSTSPQ EIRKAEYLKG YPFFNYNLYH EEGWCDVEGD LVPCPLIQDI
KRTKNTYEYR NVIQSGSSIG MLEKPYDEFV LVNANALSET QTIFPALIEK EDVTFPDYQE
ESLFHSLVYE LDYDEYTNVT WYSRKGSNVI SGVSDAIVGV IDNSEYEYLE DNSHFYGELY
GFTYPFNDFV VDPNTGEVCF TLHSDDFGHH GYEDINICVP EYEFQSPNSC TSQGGDNPPI
ELVFRKYVVK TTNITKKQYD CNYHAPIIAE MDYFPLDNKS DYRANVLKSH KIFIGVNNSP
GFRRGTSVEL TGNGKGVAKI KNELNFTGSS FTQTDLLYDG FGNVTKITSP NNLNNERLVT
NYEYETDCNQ FVKRVWNSYG DEACYKYEQR TGNLLRQVGI NGHATAYQYD GKDRLKAVYG
PREYANPGSA ATISFEYYPE GTAGGTVPVA ITSHNMGVSG TMASNPPSIN CDSDDNFSSR
PSMSQVMQTA TFIDGMSRVV QVKKDAAGNL ESSGVYSYKK VREVSGITAY DYLGRDSVTT
LSMLEDGADP ISVINTGVSS TITKSVAYDY VGKPILHVDI REQGATVQTQ IKYSWSEVNT
PFAERCFNIE TKVNSNRTYT NFINAEGQTI ARQTKGNSSG VSQFTTFEFD ALGQLLSSTD
PIELETTYGY DAFGRITYEI HPDRGRTDFT YDNAGNLIKQ KTPLTGTAGI TMDYEYNRIK
KRVMADSESK KTYNVYYSWG SEGDGKNGAG RVVSVNQGSQ NTVKEEYTFD ELGNRITEEK
QIWTLDGGTR KYDFQYKYDS WGRMREIVYP DAEILTYNYT PTGELLGMDT HHEAANPMDA
SIVDNIYYDG FGNIVQLNYS NGTTTDFEYD SYSRRLTGLN LLSGTGTLWS DNTTSRTNLL
TKDYTYDPYG NVKTVGNEAS GFDYDQTLGF ALFGIEGGEY DMQYNYDDLN RLSSASGMFD
GRPLDLSMTY DDAGGLLTKN QDFDGIAYEL EYELDTEEEL EKRKSHQINS ITDHTTTDET
IYHYDDAGNV IQIDLPNEQQ DFIWNELNHL RGVMNDNGIS HYVYDQNGER IMKGNYLSSQ
GGSNESFDIS NMTLDGYTLY VNPYYVVTNY NNTAEGSKHY YMGSQRIASG QMSYTLTPKV
DFPPESYSPT SPETPGGIVD LHDLFSKLAV RRDQAFDIDL STLLEAPELS DLKPFEAYEM
AVNESPCQTL ECRCAESIYW TEQSGEDCEA KKVMYWYHPD YLGNTEYVTN SGGLPHQFFW
YSPWGEPLVS QDLGFLSGFR SRYKFNAKEL DEETGNYYYG ARYYNPQTSV WLGVDAMAAK
YPSLSPYTFV ANNPIMLIDP DGNQIDPALL DENSPNYCAE TAQAFLDFAQ TKEGQTFLSD
YASEGQTIAG VTYSQGKYDK EGLDVKFDSK IITNKDGTIS SANGVTDVDL DGERGKITIS
LNTASTNENN SNYLSGNIGK GEYMYNLVGT ITHEAFIHGD LFAADFLDGG GFDYSNVPST
ISGSPHHYAS RRAAQNGNGR FYNQGFRIMG QMNTKYKQNY SREQIVNKMW HFRY
//
