ID G8RJD4_MYCRN Unreviewed; 368 AA.
AC G8RJD4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Methionine synthase II (Cobalamin-independent) {ECO:0000313|EMBL:AEV73504.1};
GN OrderedLocusNames=MycrhN_2949 {ECO:0000313|EMBL:AEV73504.1};
OS Mycolicibacterium rhodesiae (strain NBB3) (Mycobacterium rhodesiae).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=710685 {ECO:0000313|EMBL:AEV73504.1, ECO:0000313|Proteomes:UP000005442};
RN [1] {ECO:0000313|EMBL:AEV73504.1, ECO:0000313|Proteomes:UP000005442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBB3 {ECO:0000313|EMBL:AEV73504.1,
RC ECO:0000313|Proteomes:UP000005442};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Gu W., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T., Holmes A.,
RA Rutledge P., Paulsen I., Coleman N., Woyke T.;
RT "Complete sequence of Mycobacterium rhodesiae NBB3.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the vitamin-B12 independent methionine synthase
CC family. {ECO:0000256|ARBA:ARBA00009553}.
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DR EMBL; CP003169; AEV73504.1; -; Genomic_DNA.
DR RefSeq; WP_014211286.1; NC_016604.1.
DR AlphaFoldDB; G8RJD4; -.
DR STRING; 710685.MycrhN_2949; -.
DR KEGG; mrh:MycrhN_2949; -.
DR PATRIC; fig|710685.3.peg.2941; -.
DR eggNOG; COG0620; Bacteria.
DR HOGENOM; CLU_040013_3_1_11; -.
DR OrthoDB; 244285at2; -.
DR Proteomes; UP000005442; Chromosome.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR30519; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR PANTHER; PTHR30519:SF0; 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINE METHYLTRANSFERASE; 1.
DR Pfam; PF01717; Meth_synt_2; 2.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005442};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 10..206
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
FT DOMAIN 251..358
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 368 AA; 40729 MW; D65657B7645B4D24 CRC64;
MKVGSTDVLL PTTMVGNYPN PRWYDGHGFA QFPKGEFVYD AISREAFEDA VLAIVHDQEA
AGLDVISDGK VYGGDSPYAS IIYHYYERMS GFRPSGTNIG LPIYSTLYSP IVESEVHREH
PFHLATLRAT RKATKKPVKV SYVGIQVLAA AATNNFYSEE RELGMAIAKA FKEDFKEIEQ
NGCDIIQLDE FVWPYGIGDW EVDAINYAME GISCDFWVHT CWGNYSGTPG YLPEENEKEF
GAWVLDKRTS HSAGTERAAA IFPKVLDTNI TALNYEVGRT GPDDLKPLVD NNWNRPFVAG
VIDVKSTITE TADEVADRIR SVLEFVPAEQ LALSTDCGLI NLNRMIAASK LHALADGAAI
VRAELNQP
//
