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Database: UniProt
Entry: G8RNT6_MYCRN
LinkDB: G8RNT6_MYCRN
Original site: G8RNT6_MYCRN 
ID   G8RNT6_MYCRN            Unreviewed;       193 AA.
AC   G8RNT6;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=RNA polymerase sigma factor, sigma-70 family {ECO:0000313|EMBL:AEV73787.1};
GN   OrderedLocusNames=MycrhN_3262 {ECO:0000313|EMBL:AEV73787.1};
OS   Mycolicibacterium rhodesiae (strain NBB3) (Mycobacterium rhodesiae).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=710685 {ECO:0000313|EMBL:AEV73787.1, ECO:0000313|Proteomes:UP000005442};
RN   [1] {ECO:0000313|EMBL:AEV73787.1, ECO:0000313|Proteomes:UP000005442}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBB3 {ECO:0000313|EMBL:AEV73787.1,
RC   ECO:0000313|Proteomes:UP000005442};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Mikhailova N., Gu W., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T., Holmes A.,
RA   Rutledge P., Paulsen I., Coleman N., Woyke T.;
RT   "Complete sequence of Mycobacterium rhodesiae NBB3.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641}.
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DR   EMBL; CP003169; AEV73787.1; -; Genomic_DNA.
DR   RefSeq; WP_014211543.1; NC_016604.1.
DR   AlphaFoldDB; G8RNT6; -.
DR   STRING; 710685.MycrhN_3262; -.
DR   KEGG; mrh:MycrhN_3262; -.
DR   PATRIC; fig|710685.3.peg.3272; -.
DR   eggNOG; COG1595; Bacteria.
DR   HOGENOM; CLU_047691_9_3_11; -.
DR   OrthoDB; 9784272at2; -.
DR   Proteomes; UP000005442; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   CDD; cd06171; Sigma70_r4; 1.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR43133:SF70; ECF RNA POLYMERASE SIGMA FACTOR SIGK; 1.
DR   PANTHER; PTHR43133; RNA POLYMERASE ECF-TYPE SIGMA FACTO; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005442};
KW   Sigma factor {ECO:0000256|ARBA:ARBA00023082};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          36..102
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          139..187
FT                   /note="RNA polymerase sigma-70 region 4"
FT                   /evidence="ECO:0000259|Pfam:PF04545"
FT   REGION          100..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   193 AA;  21746 MW;  F1F597A12FE87A2B CRC64;
     MTLFPAVDRL PRVTTDLDEL LHQVARQDVD AFASFYDQTR ARVFGLVMRV LRDPGYSEET
     TQDIYLQVWR TAETYNPAAG SPLSWLMTIA HRRAVDRVRS EQAASQRESR YGAANVEPPS
     DQVADSVISG DERRQVSDCL GSLTDTQREA IQLAYYDGLT YVQVSERLSA NLATIKSRMR
     DGIRGLRRCL GLS
//
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