ID G8RP27_MYCRN Unreviewed; 502 AA.
AC G8RP27;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=NADH/NADPH-dependent glutamate synthase small subunit {ECO:0000313|EMBL:AEV75067.1};
GN OrderedLocusNames=MycrhN_4578 {ECO:0000313|EMBL:AEV75067.1};
OS Mycolicibacterium rhodesiae (strain NBB3) (Mycobacterium rhodesiae).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=710685 {ECO:0000313|EMBL:AEV75067.1, ECO:0000313|Proteomes:UP000005442};
RN [1] {ECO:0000313|EMBL:AEV75067.1, ECO:0000313|Proteomes:UP000005442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBB3 {ECO:0000313|EMBL:AEV75067.1,
RC ECO:0000313|Proteomes:UP000005442};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Gu W., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T., Holmes A.,
RA Rutledge P., Paulsen I., Coleman N., Woyke T.;
RT "Complete sequence of Mycobacterium rhodesiae NBB3.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
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DR EMBL; CP003169; AEV75067.1; -; Genomic_DNA.
DR RefSeq; WP_014212812.1; NC_016604.1.
DR AlphaFoldDB; G8RP27; -.
DR STRING; 710685.MycrhN_4578; -.
DR KEGG; mrh:MycrhN_4578; -.
DR PATRIC; fig|710685.3.peg.4586; -.
DR eggNOG; COG0493; Bacteria.
DR HOGENOM; CLU_000422_3_1_11; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000005442; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016639; F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006537; P:glutamate biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR006005; Glut_synth_ssu1.
DR InterPro; IPR009051; Helical_ferredxn.
DR NCBIfam; TIGR01317; GOGAT_sm_gam; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 2.
DR PRINTS; PR00419; ADXRDTASE.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 2.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Glutamate biosynthesis {ECO:0000256|ARBA:ARBA00023164};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000005442}.
FT DOMAIN 36..140
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 156..327
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 385..471
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 502 AA; 54270 MW; 6C43CE57A1ECB07E CRC64;
MADPTGFLKV PKVDATKRAV DERVGDWREV YEQQDPHQRA GEVSQQARRC MDCGIPFCHS
GTAGCPLGNL IPEWNDLVRR GRWDAASDRL HATNNFPEFT GRLCPAPCEA ACVLSIGEER
TGGSVTIKRI EQTIADQAWM DGIVEPQPAA IATGRRVAIV GSGPAGLAAA QQLTRAGHDV
TVYERDDRIG GLMRYGIPEY KLEKATLNQR LAQMRAEGTR FVTECEVGVD LPVEQLRQQY
DAVVLAVGAL RARDSDVEGR RLRGVHLAMD HLVPANKECE GDGASPISAA GKNVVIIGGG
DTGADCLGTA HRQGAKSVTQ LDYNPEPPEY RDESRSPWPM WPIVLRTRLS PAHAEGGDRR
YEVAVQRFLG DERGNLRAME IAEVKVERDA EGRRIITPVG ETLELPCELA LLAIGFDGVE
HMPLLDGLGL ELNRRGALPC GSDWQTDAPG VFVCGDAHRG ASLIVWAIAE GRSAAHAVDK
YLMGESDLPA PVVPGALPLA VA
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