ID G8RPX4_MYCRN Unreviewed; 531 AA.
AC G8RPX4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Acetyl-CoA carboxylase, carboxyltransferase component (Subunits alpha and beta) {ECO:0000313|EMBL:AEV73858.1};
GN OrderedLocusNames=MycrhN_3333 {ECO:0000313|EMBL:AEV73858.1};
OS Mycolicibacterium rhodesiae (strain NBB3) (Mycobacterium rhodesiae).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=710685 {ECO:0000313|EMBL:AEV73858.1, ECO:0000313|Proteomes:UP000005442};
RN [1] {ECO:0000313|EMBL:AEV73858.1, ECO:0000313|Proteomes:UP000005442}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBB3 {ECO:0000313|EMBL:AEV73858.1,
RC ECO:0000313|Proteomes:UP000005442};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Mikhailova N., Gu W., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Pagani I., Mattes T., Holmes A.,
RA Rutledge P., Paulsen I., Coleman N., Woyke T.;
RT "Complete sequence of Mycobacterium rhodesiae NBB3.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AccD/PCCB family.
CC {ECO:0000256|ARBA:ARBA00006102}.
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DR EMBL; CP003169; AEV73858.1; -; Genomic_DNA.
DR RefSeq; WP_014211614.1; NC_016604.1.
DR AlphaFoldDB; G8RPX4; -.
DR STRING; 710685.MycrhN_3333; -.
DR KEGG; mrh:MycrhN_3333; -.
DR PATRIC; fig|710685.3.peg.3342; -.
DR eggNOG; COG4799; Bacteria.
DR HOGENOM; CLU_018822_0_1_11; -.
DR OrthoDB; 9803706at2; -.
DR Proteomes; UP000005442; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR InterPro; IPR034733; AcCoA_carboxyl_beta.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011763; COA_CT_C.
DR InterPro; IPR011762; COA_CT_N.
DR InterPro; IPR045190; MCCB/AccD1-like.
DR PANTHER; PTHR22855; ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED; 1.
DR PANTHER; PTHR22855:SF46; METHYLCROTONOYL-COA CARBOXYLASE; 1.
DR Pfam; PF01039; Carboxyl_trans; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
DR PROSITE; PS50989; COA_CT_CTER; 1.
DR PROSITE; PS50980; COA_CT_NTER; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000005442};
KW Transferase {ECO:0000313|EMBL:AEV73858.1}.
FT DOMAIN 22..273
FT /note="CoA carboxyltransferase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50980"
FT DOMAIN 279..522
FT /note="CoA carboxyltransferase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50989"
SQ SEQUENCE 531 AA; 56819 MW; D91F34C83B2B62C2 CRC64;
MTALRSTVDP RSATFTEAAD VMTAKLAELD AEHAKALAGG GEKYVKRHHD RGKMTARERI
EMLLDPDSPF LELSPLAAWG SDFTVGASVV TGIGAIEGVE CLVVSNDPTV KGGTSNPWTL
KKILRANQIA LQNRLPVVSL VESGGADLPT QKEIFIPGGQ MFRDLTRLSA AGIPTIALVF
GNSTAGGAYI PGMSDHVVMI KERSKVFLAG PPLVKMATGE ESDDESLGGA EMHARTSGLG
DYFAVDELDA IRIGRRIVAR LNWRKHGPAP GPVIEPRYDP DELVGLVPAD LRIPFDPRDV
IARIVDDSDF DEFKPLYGGS LVTGWATLHG YPIGILANHR GVLFSEESQK ATQFIQLANR
ADTPLLFLHN TTGYMVGRKY EEGGMIKHGS MMINAVSNSG VPHISLLIGA SYGAGHYGMC
GRAYDPRFLF AWPSSKSAVM GGTQLAGVLS IVSRAAAEAR GQQVDEDADA ALRAAVEAQI
EAESLPMFLS GRLYDDGVID PRDTRTVLGM CLSAIANGPI KGTSNFGVFR M
//
