ID G8SK15_ACTS5 Unreviewed; 746 AA.
AC G8SK15;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Putative membrane protein mmpL11 {ECO:0000313|EMBL:AEV81914.1};
GN OrderedLocusNames=ACPL_1017 {ECO:0000313|EMBL:AEV81914.1};
OS Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=134676 {ECO:0000313|EMBL:AEV81914.1, ECO:0000313|Proteomes:UP000005440};
RN [1] {ECO:0000313|Proteomes:UP000005440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31044 / CBS 674.73 / SE50/110
RC {ECO:0000313|Proteomes:UP000005440};
RA Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K.,
RA Wehmeier U.F., Stoye J., Puehler A.;
RT "The complete genome sequence of the acarbose producer Actinoplanes sp.
RT SE50/110.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP003170; AEV81914.1; -; Genomic_DNA.
DR RefSeq; WP_014687987.1; NZ_LT827010.1.
DR AlphaFoldDB; G8SK15; -.
DR STRING; 134676.ACPL_1017; -.
DR KEGG; ase:ACPL_1017; -.
DR PATRIC; fig|134676.3.peg.909; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_5_2_11; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000005440; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005440};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 189..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 533..552
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 559..580
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 600..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 642..664
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 676..701
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 212..337
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 746 AA; 76681 MW; 7206BD4BF0B40A43 CRC64;
MLLLERMVGW SARHPKKVIV GWILLVAVAV LVGGSAGSGA KTTDAGEAGQ AQSMIRAQKV
TSSYTENVLI EAQGRDKSFL GTPDLESAAT DLSARIKALP GATSSVVTPL DNEQTRAALV
SKDGKSGLVS FTIPGPGKDA DKHFADIKKE ITAVQGAHPG VRLAMAGDIS LTSAVNKAAD
EDLSRAEQLS LPVTLIILIV VFGALVAATV PVFLAATAVL AGLGVLDLVG TIIPANSTVS
SVVLLIGMAV GTDYSLFYLR REREERAAGK SATEALKISA RTSGHAVVVS GLTVILSLAG
LFLAQVDTFN GMAIGTIIVV GLAVLGSVTV LPALLSVLGR RVDSLRVPFL GRSRTTATNS
RGWSAIAGGV SRHPLIYGGL ALIALVALAL PAFGMKLSEP GQLDSLPRSI PAVDAGVRLQ
QAFPGGADPA QVVVWGTGAT SGAADQAVAE LRREAAASDL LGDQISATPV GSVLSIKVPL
AGSGTDDTSV KALETLRTDV LPKAFANTPG LKYAVGGRTA GLHDFADVLQ QRTAWVVAFV
LVLAFIVLVV AFRAPLVAAV SMVLNLLAIG AAMGIVVLGF QKGGFAGLLG FSSFGGVVNW
LPLFMFVILF GLSMDYHVFI LSRVRERWAR GESAKDSVVH GVGSSAGVVT SAAVVMIAVF
AMFATLSGIE YKMLGVGMAV AILIDATIVR GVLLPATLSL LGDRAWSLRG RPAVVTGSDP
VAESAHAEPT EEAVLVSHAA ATARGE
//
