ID G8SKB9_ACTS5 Unreviewed; 701 AA.
AC G8SKB9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=phy1 {ECO:0000313|EMBL:AEV84428.1};
GN OrderedLocusNames=ACPL_3533 {ECO:0000313|EMBL:AEV84428.1};
OS Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=134676 {ECO:0000313|EMBL:AEV84428.1, ECO:0000313|Proteomes:UP000005440};
RN [1] {ECO:0000313|Proteomes:UP000005440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31044 / CBS 674.73 / SE50/110
RC {ECO:0000313|Proteomes:UP000005440};
RA Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K.,
RA Wehmeier U.F., Stoye J., Puehler A.;
RT "The complete genome sequence of the acarbose producer Actinoplanes sp.
RT SE50/110.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP003170; AEV84428.1; -; Genomic_DNA.
DR AlphaFoldDB; G8SKB9; -.
DR STRING; 134676.ACPL_3533; -.
DR KEGG; ase:ACPL_3533; -.
DR PATRIC; fig|134676.3.peg.3448; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_114_44_11; -.
DR Proteomes; UP000005440; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF01590; GAF; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AEV84428.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000005440};
KW Transferase {ECO:0000313|EMBL:AEV84428.1}.
FT DOMAIN 466..679
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 678..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 701 AA; 74731 MW; 1A323BB399638CC7 CRC64;
MAVLSLVGAE QEEFLGMFGL PASPAARRRT GEHLVCANVV AADGPLAVPD MTADPQFAEH
PAFTGHGIRA FAGVPLRDGQ DRQVGALSVL DDGPHDWSET DLSTLVEITA MLGPVPVGAD
PVIAMAALTD LDQSGSAADA PAAAVSATVH AEVQAGFITA LLDSLQVGVF AVDTDRRPVL
FNRTLRQFYG LPEDLTPAEA MAGAYTQLRH LDGTPYATDE LATVRALREG SVRDVRAVMQ
APDMPDRHIL TNAEAIHDAA GHLLGAVATV QDVTDRRRRE RFRDCELRVA GILNRCDTIA
EAAPPILRAV GEALHWQYLA LLLIDEVADV LRVAACWSAP GVEVGGLLPD MIGRGDAETR
RLGRTDQPLP LSDLVDSHLI ARHAAQTIAR AAADQGLRAS LAVPIRDADT ILGVLVSLSS
TAECDRVLLA GLLTSVTAQL GQFLIHRRNA ELQAQLVHAK DDFLTLVGHE MRTPLTSIIS
YSTLLADELI EPELGAVVAA ITRNTSTLQS IIDELLDLAG LEAGNTSLQL RPTHLTEIVN
AAVTAVPVDA QRRIHTDMPP TLLVEADPHR LRQIIDHLLS NAIKYSPDGG DIRISAHEHD
TGVVELAVVD PGIGIPAEDH QQLFTRFHRA GNTRHSYIPG TGLGLALVRA LVHAHGGTIT
YDPHHRPGTR ITLRLPQHHS GAGKPGNAVP GSGTLNGYRT T
//
