ID G8SL56_ACTS5 Unreviewed; 874 AA.
AC G8SL56;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Putative signaling protein {ECO:0000313|EMBL:AEV88261.1};
GN OrderedLocusNames=ACPL_7381 {ECO:0000313|EMBL:AEV88261.1};
OS Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110).
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=134676 {ECO:0000313|EMBL:AEV88261.1, ECO:0000313|Proteomes:UP000005440};
RN [1] {ECO:0000313|Proteomes:UP000005440}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 31044 / CBS 674.73 / SE50/110
RC {ECO:0000313|Proteomes:UP000005440};
RA Schwientek P., Szczepanowski R., Kalinowski J., Klein A., Selber K.,
RA Wehmeier U.F., Stoye J., Puehler A.;
RT "The complete genome sequence of the acarbose producer Actinoplanes sp.
RT SE50/110.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003170; AEV88261.1; -; Genomic_DNA.
DR RefSeq; WP_014694322.1; NZ_LT827010.1.
DR AlphaFoldDB; G8SL56; -.
DR STRING; 134676.ACPL_7381; -.
DR KEGG; ase:ACPL_7381; -.
DR PATRIC; fig|134676.3.peg.7300; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_129_3_11; -.
DR Proteomes; UP000005440; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00989; PAS; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005440};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 324..394
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 481..611
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 620..869
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 874 AA; 92017 MW; 2DDB818220A191DB CRC64;
MAVSPLAPAR PSNTGRAALL AVCSAAALVL LTGVFGLLPG PLTLAVGVGV AGLCASAYLV
HAALDIHHAD GTFVACRGAG FVGMGALATA LTALIPWWSP PHAVLWLTAG LGVAAGCYVL
GAALLPNAAR TWPIRLRRGF DGLGLGVSLG YAAYLIPPDG QTRPAALPAL LITAGGVSIV
TVVVLRARPR PVPTVWCGCG AAVVLAALAA LAEVLALGLT GPAVPLLGLA MVAGLAAAAG
GGSRRGLPVP PAEPRSPDQY LASYPLLAVP AVVGVAAALW HLVTTRHFDA GGIVFGMVMV
SVLVLRELLV VRDIRRYAGR LRIAEAHFRS LVAGATDLTL VLDDRLTVRW QSPAAARLFG
LHDNEVVGRA FGDLIHPEDA GDALAVIGSV LAGEHEGGPP VLVSARLRDG SQLWRDTEST
ISDQRAVPEV AALVVHVRDV GERRHLERTL HRMAYLDQLT GLANRRALMR DLLAARRRPG
GPGTLLVIDL HGLAEVNDTH GRAVGDAVLT EVARRLRALS GGEDVPARLA GDEFAVLTPE
SAVPAYALAT RLVSALAEPC QLPGAQVRLH TSVGLAELAG AAGPEEVLRQ ADLARQRAAQ
LGRDAVEWYD PDVELHLQRR MELERQLPGA AARGELDLVF QPVSDLRDGH PAGVEALLRW
RHPALGTIRP EEFLPIAAGL GITDTLNEWA LNDACRHLRN WTGGDDDFWV SVNVGPRELL
TARFPEQVRT TLRRHAVTPE RLVVEVAQTW IAEDVPAVVA ALAGLRRLGV RAALDDFGSS
QTSLTHLRRL PVDMVKLSAE LAGAEAGKPV LDVVVGLAKR IGLDLVAKGL ETPEQIERVL
AAGCRYGQGT ALVPPAPAER IEAYLETHRA DRGS
//
