ID G8TJN4_NIAKG Unreviewed; 455 AA.
AC G8TJN4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Cystathionine beta-synthase {ECO:0000313|EMBL:AEW00781.1};
DE EC=4.2.1.22 {ECO:0000313|EMBL:AEW00781.1};
GN OrderedLocusNames=Niako_4523 {ECO:0000313|EMBL:AEW00781.1};
OS Niastella koreensis (strain DSM 17620 / KACC 11465 / NBRC 106392 /
OS GR20-10).
OC Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC Niastella.
OX NCBI_TaxID=700598 {ECO:0000313|EMBL:AEW00781.1, ECO:0000313|Proteomes:UP000005438};
RN [1] {ECO:0000313|EMBL:AEW00781.1, ECO:0000313|Proteomes:UP000005438}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17620 / KACC 11465 / NBRC 106392 / GR20-10
RC {ECO:0000313|Proteomes:UP000005438};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Davenport K.,
RA Saunders E., Detter J.C., Tapia R., Han C., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B.,
RA Pomrenke H., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Niastella koreensis GR20-10.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; CP003178; AEW00781.1; -; Genomic_DNA.
DR RefSeq; WP_014220693.1; NC_016609.1.
DR AlphaFoldDB; G8TJN4; -.
DR STRING; 700598.Niako_4523; -.
DR KEGG; nko:Niako_4523; -.
DR PATRIC; fig|700598.3.peg.4630; -.
DR eggNOG; COG0031; Bacteria.
DR eggNOG; COG3620; Bacteria.
DR HOGENOM; CLU_021018_0_0_10; -.
DR OrthoDB; 9808024at2; -.
DR Proteomes; UP000005438; Chromosome.
DR GO; GO:0004122; F:cystathionine beta-synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0019344; P:cysteine biosynthetic process; IEA:UniProt.
DR CDD; cd01561; CBS_like; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR PANTHER; PTHR10314:SF194; CYSTATHIONINE BETA-SYNTHASE; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00291; PALP; 1.
DR SMART; SM00116; CBS; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:AEW00781.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898}.
FT DOMAIN 340..396
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 455 AA; 50456 MW; 5347E86B9674B8C4 CRC64;
MDIKSNILET IGNTPLIKLN KITRQFPATV VAKVDYFNPG NSIKDRMAVK MIEVAEKEGK
LKPGGTIIEC TSGNTGMGLA LAACVKGYKC IFTTTDKQSK EKVDILKAVG AEVIVCPTNV
EPDDPRSYYS VARRLAKEIP NSFHCNQYDN LASRLAHYET TGPEIWKQTD GKITHLVCTA
GTGGTVTGTA MYLKEKNPNI KIWAIDVYGS LLTKYFRTGK VDMKEVHPYI SEGFGEDFVP
ENYDMSVIDH FEQVTDRDGA IMARRLAKDE GLFCGYSAGS CLQGLMQIAA NEPLKKDDLV
VCIFHDHGSR YVAKIYNDQW MMERGFMDVK TFKDIINGRT GKQKLVTIEP NRTVAQAVEL
MRKYDIEHIP VINGSGPVGA ISESGLFQKI FSNPDIKNAT IETVMEPAYP IVDLNTPIEK
LRTLINKDNG AVLSKDELGN YHIVTKYDVI LALGS
//
