ID G8TU52_SULAD Unreviewed; 732 AA.
AC G8TU52;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:AEW05724.1};
GN OrderedLocusNames=Sulac_2251 {ECO:0000313|EMBL:AEW05724.1};
OS Sulfobacillus acidophilus (strain ATCC 700253 / DSM 10332 / NAL).
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Clostridiales Family XVII. Incertae Sedis; Sulfobacillus.
OX NCBI_TaxID=679936 {ECO:0000313|EMBL:AEW05724.1, ECO:0000313|Proteomes:UP000005439};
RN [1] {ECO:0000313|Proteomes:UP000005439}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700253 / DSM 10332 / NAL
RC {ECO:0000313|Proteomes:UP000005439};
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Chertkov O.,
RA Saunders E., Detter J.C., Tapia R., Han C., Land M., Hauser L.,
RA Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Pukall R.,
RA Gehrich-Schroeter G., Schneider S., Klenk H.-P., Eisen J.A.;
RT "The complete genome of chromosome of Sulfobacillus acidophilus DSM
RT 10332.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEW05724.1, ECO:0000313|Proteomes:UP000005439}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700253 / DSM 10332 / NAL
RC {ECO:0000313|Proteomes:UP000005439};
RX PubMed=23407703; DOI=10.4056/sigs.2736042;
RA Anderson I., Chertkov O., Chen A., Saunders E., Lapidus A., Nolan M.,
RA Lucas S., Hammon N., Deshpande S., Cheng J.F., Han C., Tapia R.,
RA Goodwin L.A., Pitluck S., Liolios K., Pagani I., Ivanova N., Mikhailova N.,
RA Pati A., Palaniappan K., Land M., Pan C., Rohde M., Pukall R., Goker M.,
RA Detter J.C., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P., Mavromatis K.;
RT "Complete genome sequence of the moderately thermophilic mineral-sulfide-
RT oxidizing firmicute Sulfobacillus acidophilus type strain (NAL(T)).";
RL Stand. Genomic Sci. 6:1-13(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003179; AEW05724.1; -; Genomic_DNA.
DR AlphaFoldDB; G8TU52; -.
DR STRING; 679936.Sulac_2251; -.
DR KEGG; sap:Sulac_2251; -.
DR PATRIC; fig|679936.5.peg.2331; -.
DR HOGENOM; CLU_378511_0_0_9; -.
DR Proteomes; UP000005439; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 2.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR32347; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR PANTHER; PTHR32347:SF14; EFFLUX SYSTEM COMPONENT YKNX-RELATED; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR Pfam; PF13437; HlyD_3; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005439};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 76..125
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT COILED 117..213
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 335..470
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 732 AA; 75029 MW; 69BB087EABBDD6A5 CRC64;
MVTTPQRRGL NLLALGHANR WVLYGGAAVI VVGGGLIYRA ATKHNVAIPA SDIYTVGYGS
VVQTISASGT VEPLQQVNLN FPAGGGILST VNVKVGQAVK AGQVLATLSD PSAQAAIQSA
EAAVASAEAN LASLQAGPTP QAIAVDQANV QHAQIQLAGA EQQYQDAQQS LAASAQQTLD
NAQNQVAEDN AALQAAQANV ASAQNKLQQA EAGVSTSTVN SLPATISSDQ QALKADQAQL
AADQQTLSNA QQTLQQDQTT LQQDQSLYGT LASQYPQDEQ AYQQALENYN SWSGYGTNPY
QSLVNSTQVA ASAAQNAYNT LQSIKTQVAS DQAAVLEAQK QVAADQAAIQ NAQAALTQAE
DQQANLNQTN PLTVQAAQVA LQQAQASLAQ AQAAYQGAVN SVSVTKSVTQ ASDQSQLDQL
KSTVQLDQNA VTQAEDALNE AQAPPTPAQL AAAEAQVQSA KAQLASAQAE ASNDILKAPF
NGVIVASNYN PGDTVSSATP VFVLDNTIKN DLEAQVEVAE ADIGQVKAGE SVALTASAYP
NQTFTGKVFE VEPNPQTVDN VTEYTVLTTV NNPGGLLLPG MTTNVTINTG EVNHVLTVPP
VALQTLGSTQ GVYVMASSFK LGAFHPNPAL LKKFKKLHAG TAGGGFVHRT GASSGVVFIP
VQVGLFGTNS VQVTRGVFPG EKILLVPPSS LNIQARGGFL FGGGRGGFGG GGGRFNSGGS
GAGASIGGTG GQ
//
