ID   G8UN85_TANFA            Unreviewed;       493 AA.
AC   G8UN85;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=O-Glycosyl hydrolase family 30 {ECO:0000313|EMBL:AEW22095.1};
GN   OrderedLocusNames=BFO_2803 {ECO:0000313|EMBL:AEW22095.1};
OS   Tannerella forsythia (strain ATCC 43037 / JCM 10827 / CCUG 21028 A / KCTC
OS   5666 / FDC 338) (Bacteroides forsythus).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC   Tannerella.
OX   NCBI_TaxID=203275 {ECO:0000313|EMBL:AEW22095.1, ECO:0000313|Proteomes:UP000005436};
RN   [1] {ECO:0000313|Proteomes:UP000005436}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43037 / JCM 10827 / CCUG 33226 / KCTC 5666 / FDC 338
RC   {ECO:0000313|Proteomes:UP000005436};
RA   Dewhirst F., Tanner A., Izard J., Brinkac L., Durkin A.S., Hostetler J.,
RA   Shetty J., Torralba M., Gill S., Nelson K.;
RT   "Complete sequence of Tannerella forsythia ATCC 43037.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382, ECO:0000256|RuleBase:RU361188}.
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DR   EMBL; CP003191; AEW22095.1; -; Genomic_DNA.
DR   AlphaFoldDB; G8UN85; -.
DR   STRING; 203275.BFO_2803; -.
DR   KEGG; tfo:BFO_2803; -.
DR   PATRIC; fig|203275.8.peg.2402; -.
DR   eggNOG; COG5520; Bacteria.
DR   HOGENOM; CLU_014379_4_0_10; -.
DR   Proteomes; UP000005436; Chromosome.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF02055; Glyco_hydro_30; 2.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU361188};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361188};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005436};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..493
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003517242"
FT   DOMAIN          79..175
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   DOMAIN          222..424
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
SQ   SEQUENCE   493 AA;  57500 MW;  D94F382093BB9515 CRC64;
     MKRFSKRILM FSCLAMSVSN LYAQSYTWFC STENDVWKET KIKLQSKSET APILKVTGAE
     SIQIFKRWGT CFNELGWDAL NLLSLEQQDA ILSKLFSPDG ELHFSMGRIP MNANDYARDW
     YSCDEVDGDF QLKYFNIDRD KKTIIPFIRK ALHYNPNMTF WASPWSPPSW MKVNHYYSIL
     SNDKVNKMSP LSNVILHENS TERNDAYYPK QLAVNDYFIQ DTRYLRTYAD YFCRFISAYQ
     DENIPVTKVM FQNEPWAFTI YPGCAWTPEG IIRFNVEYLA PELEKRHPDV SLYLGTLNTN
     RFEIVDKILS DPRMHKTVDG LGFQWWGGQI LPDIRKKYPH YKYMQTENEC GSGTFDWKAA
     EHTFNLINHY LGNGCEEYTF WNAILCDEGT SGWGWKQNAL IHVDSKTEAV TYTPEYYAVR
     HFSDKVTSGT KVLQYKEKGD DKLPAMVFLT SDNKYLVVAG NFNDEPRKLT IQLGAKFLVA
     TLKPHSFNSF YMK
//