ID G8XBC2_FLACA Unreviewed; 243 AA.
AC G8XBC2;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Phospholipid/glycerol acyltransferase {ECO:0000313|EMBL:AEW86702.1};
GN OrderedLocusNames=FCOL_09465 {ECO:0000313|EMBL:AEW86702.1};
OS Flavobacterium columnare (strain ATCC 49512 / CIP 103533 / TG 44/87).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1041826 {ECO:0000313|EMBL:AEW86702.1, ECO:0000313|Proteomes:UP000005638};
RN [1] {ECO:0000313|Proteomes:UP000005638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49512 / CIP 103533 / TG 44/87
RC {ECO:0000313|Proteomes:UP000005638};
RA Tekedar H.C., Karsi A., Gillaspy A.F., Dyer D., Benton N.R., Zaitshik J.,
RA Vamenta S., Banes M.M., Gulsoy N., Aboko-Cole M., Waldbieser G.C.,
RA Lawrence M.L.;
RT "Complete genome sequence of Flavobacterium columnare ATCC 49512.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEW86702.1, ECO:0000313|Proteomes:UP000005638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49512 / CIP 103533 / TG 44/87
RC {ECO:0000313|Proteomes:UP000005638};
RX PubMed=22535941; DOI=10.1128/JB.00281-12;
RA Tekedar H.C., Karsi A., Gillaspy A.F., Dyer D.W., Benton N.R., Zaitshik J.,
RA Vamenta S., Banes M.M., Gulsoy N., Aboko-Cole M., Waldbieser G.C.,
RA Lawrence M.L.;
RT "Genome Sequence of the Fish Pathogen Flavobacterium columnare ATCC
RT 49512.";
RL J. Bacteriol. 194:2763-2764(2012).
CC -!- FUNCTION: Converts lysophosphatidic acid (LPA) into phosphatidic acid
CC by incorporating acyl moiety at the 2 position.
CC {ECO:0000256|ARBA:ARBA00037183}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-
CC sn-glycero-3-phosphate + CoA; Xref=Rhea:RHEA:19709,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57970, ChEBI:CHEBI:58342,
CC ChEBI:CHEBI:58608; EC=2.3.1.51;
CC Evidence={ECO:0000256|ARBA:ARBA00001141};
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DR EMBL; CP003222; AEW86702.1; -; Genomic_DNA.
DR RefSeq; WP_014165976.1; NC_016510.2.
DR AlphaFoldDB; G8XBC2; -.
DR STRING; 1041826.FCOL_09465; -.
DR GeneID; 60758529; -.
DR KEGG; fco:FCOL_09465; -.
DR eggNOG; COG0204; Bacteria.
DR HOGENOM; CLU_027938_6_4_10; -.
DR Proteomes; UP000005638; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd07989; LPLAT_AGPAT-like; 1.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR PANTHER; PTHR10434; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE; 1.
DR PANTHER; PTHR10434:SF60; 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE LPAT1, CHLOROPLASTIC; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
DR SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:AEW86702.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005638};
KW Transferase {ECO:0000313|EMBL:AEW86702.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 76..195
FT /note="Phospholipid/glycerol acyltransferase"
FT /evidence="ECO:0000259|SMART:SM00563"
SQ SEQUENCE 243 AA; 28193 MW; 406DAFDA3D916843 CRC64;
MLKLISYPLS ILFGILFFLW LLLFHPIQWF CLKFFGYNTH RISVAILNAF LVRTTHVLGT
TYKIKGIENI PKNKPLIIVA NHQSLYDIPP FIWFLRKYHP KFISKKELGK KIPSVSFNLR
HGGSALIDRK DPKQALPEIK RVAEYINQNN YSVVIFPEGT RSKTGVPKPF SINGLKMLYK
FAPDAYFLPV TINNSWKMTR YGQFPLGLGS NIEHIIHPPL KISDYSFDDI FKKTETIIKE
HIK
//
