ID G8Y1N0_PICSO Unreviewed; 304 AA.
AC G8Y1N0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU369086};
GN Name=Piso0_005242 {ECO:0000313|EMBL:CCE86733.1};
GN ORFNames=GNLVRS01_PISO0N10859g {ECO:0000313|EMBL:CCE86733.1};
OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS 10061 / NRRL Y-12695) (Hybrid yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE86733.1, ECO:0000313|Proteomes:UP000005222};
RN [1] {ECO:0000313|Proteomes:UP000005222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
CC -!- FUNCTION: DNA-dependent RNA polymerase which catalyzes the
CC transcription of DNA into RNA using the four ribonucleoside
CC triphosphates as substrates. {ECO:0000256|RuleBase:RU369086}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the eukaryotic RPA43 RNA polymerase subunit
CC family. {ECO:0000256|ARBA:ARBA00005930}.
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DR EMBL; FO082046; CCE86733.1; -; Genomic_DNA.
DR AlphaFoldDB; G8Y1N0; -.
DR STRING; 559304.G8Y1N0; -.
DR eggNOG; KOG4134; Eukaryota.
DR HOGENOM; CLU_060987_0_0_1; -.
DR InParanoid; G8Y1N0; -.
DR OMA; YMQTASH; -.
DR Proteomes; UP000005222; Chromosome N.
DR GO; GO:0055029; C:nuclear DNA-directed RNA polymerase complex; IEA:UniProt.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:UniProtKB-UniRule.
DR CDD; cd04328; RNAP_I_Rpa43_N; 1.
DR Gene3D; 2.40.50.1060; -; 1.
DR Gene3D; 3.30.1490.120; RNA polymerase Rpb7-like, N-terminal domain; 1.
DR InterPro; IPR036898; RNA_pol_Rpb7-like_N_sf.
DR InterPro; IPR041901; RNAP_I_Rpa43_N.
DR InterPro; IPR041178; RPA43_OB.
DR InterPro; IPR045113; Rpb7-like.
DR InterPro; IPR005576; Rpb7-like_N.
DR PANTHER; PTHR12709:SF5; DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43; 1.
DR PANTHER; PTHR12709; DNA-DIRECTED RNA POLYMERASE II, III; 1.
DR Pfam; PF17875; RPA43_OB; 1.
DR Pfam; PF03876; SHS2_Rpb7-N; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU369086};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU369086};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000005222};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU369086}.
FT DOMAIN 46..94
FT /note="RNA polymerase Rpb7-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03876"
FT DOMAIN 130..228
FT /note="RPA43 OB"
FT /evidence="ECO:0000259|Pfam:PF17875"
FT REGION 228..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..294
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 304 AA; 34217 MW; 72A15A5C14B70C79 CRC64;
MVEKRQHNQA NASSVPRKRK QFLFPKSSNP LNDEGVSECF HKITTSLYLS LAPSHLSDPI
NGIKSQHLDH LIMSYYPKVQ GVIIAYSNIK LAGEESFEDV SEESTPIVKV SATSPFTFMW
VNVDFMVWKP QVGDVLEGYI YMQTPSHIGL LLHDTFNASI KKYNIPQTWR FVPNQEDEFA
EDTKSSGTFK SYGYWVNEND LKVEGKLKFS VKSIHTTGRV VSVDGTLIEP GSEKDSQPII
RDRRSSTDAE VEAPSNKHKK FDDDVATITE IPEQKEEILE SLPHYSKTSD TDDESTGSQD
SSSS
//
