ID G8Y762_PICSO Unreviewed; 993 AA.
AC G8Y762;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Piso0_003986 protein {ECO:0000313|EMBL:CCE84442.1};
GN Name=Piso0_003986 {ECO:0000313|EMBL:CCE84442.1};
GN ORFNames=GNLVRS01_PISO0K06940g {ECO:0000313|EMBL:CCE83411.1},
GN GNLVRS01_PISO0L06941g {ECO:0000313|EMBL:CCE84442.1};
OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS 10061 / NRRL Y-12695) (Hybrid yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE84442.1, ECO:0000313|Proteomes:UP000005222};
RN [1] {ECO:0000313|EMBL:CCE84442.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000005222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
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DR EMBL; FO082049; CCE83411.1; -; Genomic_DNA.
DR EMBL; FO082048; CCE84442.1; -; Genomic_DNA.
DR AlphaFoldDB; G8Y762; -.
DR STRING; 559304.G8Y762; -.
DR eggNOG; KOG0468; Eukaryota.
DR HOGENOM; CLU_002794_11_2_1; -.
DR InParanoid; G8Y762; -.
DR OMA; THGQAFP; -.
DR Proteomes; UP000005222; Chromosome K.
DR Proteomes; UP000005222; Chromosome L.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR CDD; cd04090; EF2_II_snRNP; 1.
DR CDD; cd01683; EF2_IV_snRNP; 1.
DR CDD; cd04167; Snu114p; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR Gene3D; 3.90.1430.10; Yeast translation eEF2 (G' domain); 1.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR031950; EFTUD2_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR044121; Snu114_GTP-bd.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF6; 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF16004; EFTUD2; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005222}.
FT DOMAIN 153..430
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 993 AA; 111495 MW; 316E52A1C050CFAE CRC64;
MDDDLYDEFG NPIGGQDDEQ FDSESSNASN LAHSDDEASE SGVDDEMRND EAETNLVLHA
DAGKEHTIED VDADSHKALS LKTVYGKGVE TIVASEDVPM EDEPVIKPLT ETKMKVEYTD
FEDDQDGISP SRGIPEVTYS REYMLSIMNS MPERVRNISI VGNLHSGKST FVDMFVLQTH
PGITTPDNAS NNFKPLRYLD NHKLEIQRGI TIKSSPITLL LSDPRDRSYI FNFVDTPGHI
NFNDEVVASL AGTDGAVVII DVVEGVTYRD HIIISDLLRL NVPFVVSLNK IDRLIMELKL
PPADAYHKMQ NIIDDLNSFI ISNEYVASYR FDKEYSPIHG NVMFSSANFN LCFTLNSFAA
LYQFDKGDQA YLERLWGDFY YNPHNNSFTR SSNDGNFQRT FVAFILNPLY KLFTYTITAD
SSDKRLPSLL WSNFRVNLDK SVYKKDPQIL LRYILRAIFP NASGFVESVA KCIPSPESFF
KKRYENNKLP QSNYKGVPMA QVLKLIENSN GKGFVSLVRI YHGSLKVGDR VKVLGENFDE
DQDDYKLEIV DAIFLAGGRY KIPIKNAPLG SLVLISGVDS IINKTATICN TNDTDLLWTF
PRHNFEIKSV LKVAVEPSNP SELPKLIESL RQVSKSYLAC SIKVEDSGEH VILAPGEIYM
DCLLHDLRFF FADDLEIKVS DLSTKFSETC ADISAIKITS RSQSRENAIS ITAEPVGDQK
LSYAIEKGVI SLSNPPEETS NALSKDFGWD ILASKSVWCF GPDDLNSPDI LMDDTIEGET
DKTALFSIKD SINLGFKWSV NEGPLCDEPI RNTKFKILDA VVSGSEIKRN GTQVIPMTRK
ACYSGFLTAS PRLMEPIYSV FITTTFKAIR AVDGLLRKRR GKLIEEYPIP ATPLYTLRGH
IPVIESVGFE SDLRAQTQGQ AMCLLDFEKW KIVPGDPLDQ ECFLPPLQPV PTESLARDFV
LKTRRRKGLS GEPSLRKYIE PELYNKLVEN SLI
//
