ID G8YHA4_PICSO Unreviewed; 673 AA.
AC G8YHA4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Piso0_003138 protein {ECO:0000313|EMBL:CCE80806.1};
GN Name=Piso0_003138 {ECO:0000313|EMBL:CCE80806.1};
GN ORFNames=GNLVRS01_PISO0G05726g {ECO:0000313|EMBL:CCE80041.1},
GN GNLVRS01_PISO0H05727g {ECO:0000313|EMBL:CCE80806.1};
OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC
OS 10061 / NRRL Y-12695) (Hybrid yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Millerozyma.
OX NCBI_TaxID=559304 {ECO:0000313|EMBL:CCE80806.1, ECO:0000313|Proteomes:UP000005222};
RN [1] {ECO:0000313|EMBL:CCE80806.1}
RP NUCLEOTIDE SEQUENCE.
RA Genoscope - CEA;
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000005222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL
RC Y-12695 {ECO:0000313|Proteomes:UP000005222};
RX DOI=10.1534/g3.111.000745;
RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P.,
RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A.,
RA Straub M.L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S.,
RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., Mallet S.,
RA Morel G., Richard G.F., Sarkar A., Savel G., Schacherer J., Seret M.L.,
RA Talla E., Samson G., Jubin C., Poulain J., Vacherie B., Barbe V.,
RA Pelletier E., Sherman D.J., Westhof E., Weissenbach J., Baret P.V.,
RA Wincker P., Gaillardin C., Dujon B., Souciet J.L.;
RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps of
RT genome resolution following polyploidization.";
RL G3 (Bethesda) 2:299-311(2012).
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; FO082053; CCE80041.1; -; Genomic_DNA.
DR EMBL; FO082052; CCE80806.1; -; Genomic_DNA.
DR AlphaFoldDB; G8YHA4; -.
DR STRING; 559304.G8YHA4; -.
DR eggNOG; KOG2273; Eukaryota.
DR HOGENOM; CLU_014456_2_0_1; -.
DR InParanoid; G8YHA4; -.
DR Proteomes; UP000005222; Chromosome G.
DR Proteomes; UP000005222; Chromosome H.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR46979; SORTING NEXIN-41; 1.
DR PANTHER; PTHR46979:SF2; SORTING NEXIN-41; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000005222}.
FT DOMAIN 107..270
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 530..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..60
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 673 AA; 76664 MW; F1FC397A05C84E05 CRC64;
MSDKNENNMD QGIADFEEED NNPFPHIKGL ASLMSEHRLY DSDDKEGTSG GEKAKQMDDD
PSVLLYKSNK QSNENKDILS GDTFKSIQIN YESRVTRLLR PNSKISINII KAGSSNEGMI
NSSKTYIVYT IQLLNNDDPG DEIQTRRRYS DFESLREILT KIYPLIIIPP IPPKNYSKFS
VFSGIVGTNT TSNSSMNSPE SNNLSGDYDG GPTSISNKYS YINSTHLNKS KLIEHRKRLL
SNFLNNCLSI PQIRNLEFFA KFLDPNANWS DETALISNQL PKSIYHSNPE NGLKTDPLYD
NLPNPSNSHA LNISFLKSLQ ENRRKLSIKG RKSKTGTTEE EPVNEASDSV KSSGSKDIID
PTRSDMIIDT SYLDSTNEKI MINFMGLAND YTELGTIFNS FSLVLSDSPI IRTAKAKGVD
DYDSKLNIIF DKIGQVFDRS YVATNALIAE LETKFSEPLG EAVQFTNILE FIQKFQRRKV
KQQELVETEL EDKKHELHDL TRAEAESSRI DDVLHSRVIS KDSNFDFSDA ASNDNYANEN
NNASDANKQQ DKGKSKKNNS KFSSKTKYLS SINSFKKITQ YVSEIIDQNP EETRKTKIVN
IRKRIEILEK CSTIMIQDLS YIADEIEKNF TLFHKKQIRD MYEILLRYNG FLVGWAKKNL
DIWEEVKEEL ERL
//
