ID   G9CNQ9_RALSL            Unreviewed;       245 AA.
AC   G9CNQ9;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=leucine--tRNA ligase {ECO:0000256|ARBA:ARBA00013164};
DE            EC=6.1.1.4 {ECO:0000256|ARBA:ARBA00013164};
DE   Flags: Fragment;
GN   Name=leuS {ECO:0000313|EMBL:AEV53129.1};
OS   Ralstonia solanacearum (Pseudomonas solanacearum).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=305 {ECO:0000313|EMBL:AEV53129.1};
RN   [1] {ECO:0000313|EMBL:AEV53129.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MAFF301558 {ECO:0000313|EMBL:AEV53129.1};
RA   Wicker E.P.P., Lefeuvre P., De Cambiaire J.-C., Lemaire C., Poussier S.,
RA   Prior P.;
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AEV53129.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MAFF301558 {ECO:0000313|EMBL:AEV53129.1};
RX   PubMed=22094345; DOI=10.1038/ismej.2011.160;
RA   Wicker E., Lefeuvre P., de Cambiaire J.C., Lemaire C., Poussier S.,
RA   Prior P.;
RT   "Contrasting recombination patterns and demographic histories of the plant
RT   pathogen Ralstonia solanacearum inferred from MLSA.";
RL   ISME J. 6:961-974(2012).
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363039}.
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DR   EMBL; JF702622; AEV53129.1; -; Genomic_DNA.
DR   AlphaFoldDB; G9CNQ9; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004823; F:leucine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006429; P:leucyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd00812; LeuRS_core; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR   InterPro; IPR002302; Leu-tRNA-ligase.
DR   InterPro; IPR015413; Methionyl/Leucyl_tRNA_Synth.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR43740:SF2; LEUCINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43740; LEUCYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF09334; tRNA-synt_1g; 1.
DR   PRINTS; PR00985; TRNASYNTHLEU.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000256|RuleBase:RU363039};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363039};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363039};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU363039};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW   ECO:0000256|RuleBase:RU363039}.
FT   DOMAIN          27..160
FT                   /note="Methionyl/Leucyl tRNA synthetase"
FT                   /evidence="ECO:0000259|Pfam:PF09334"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AEV53129.1"
FT   NON_TER         245
FT                   /evidence="ECO:0000313|EMBL:AEV53129.1"
SQ   SEQUENCE   245 AA;  28047 MW;  96C859475BC6D366 CRC64;
     WQAQDAYRVT EHARAADGSD KPKFYACSML PYPSGKLHMG HVRNYTINDV MTRQLRMKGY
     NVLMPMGWDA FGMPAENAAL NNGVAPAAWT YDNIAYMKKQ MQSMGLAIDW SREVATCNPD
     YYKWNQWLFL KMLEKGIAYR KTGTVNWDPV DQTVLANEQV IDGRGWRSGA VVEKREIPMY
     YLRITDYAQE LLSDLDPLGW PERVKLMQQN WIGKSEGVRF AFPHGIPGDD GKVIGDGKLY
     VFTTR
//