ID G9ETL1_9GAMM Unreviewed; 454 AA.
AC G9ETL1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Cytosol aminopeptidase domain-containing protein {ECO:0000259|PROSITE:PS00631};
GN ORFNames=LDG_8644 {ECO:0000313|EMBL:EHL29678.1};
OS Legionella drancourtii LLAP12.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=658187 {ECO:0000313|EMBL:EHL29678.1, ECO:0000313|Proteomes:UP000002770};
RN [1] {ECO:0000313|EMBL:EHL29678.1, ECO:0000313|Proteomes:UP000002770}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LLAP12 {ECO:0000313|EMBL:EHL29678.1,
RC ECO:0000313|Proteomes:UP000002770};
RX PubMed=22047552; DOI=10.1186/1471-2164-12-542;
RA Gimenez G., Bertelli C., Moliner C., Robert C., Raoult D., Fournier P.E.,
RA Greub G.;
RT "Insight into cross-talk between intra-amoebal pathogens.";
RL BMC Genomics 12:542-542(2011).
CC -!- SIMILARITY: Belongs to the peptidase M17 family.
CC {ECO:0000256|ARBA:ARBA00009528}.
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DR EMBL; JH413847; EHL29678.1; -; Genomic_DNA.
DR RefSeq; WP_006872515.1; NZ_JH413847.1.
DR AlphaFoldDB; G9ETL1; -.
DR STRING; 658187.LDG_8644; -.
DR eggNOG; COG0260; Bacteria.
DR HOGENOM; CLU_013734_2_1_6; -.
DR InParanoid; G9ETL1; -.
DR OrthoDB; 9809354at2; -.
DR Proteomes; UP000002770; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00433; Peptidase_M17; 1.
DR Gene3D; 3.40.220.10; Leucine Aminopeptidase, subunit E, domain 1; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR011356; Leucine_aapep/pepB.
DR InterPro; IPR043472; Macro_dom-like.
DR InterPro; IPR000819; Peptidase_M17_C.
DR InterPro; IPR048816; Peptidase_M17_N_1.
DR PANTHER; PTHR11963:SF53; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR Pfam; PF00883; Peptidase_M17; 1.
DR Pfam; PF21337; Peptidase_M17_N_1; 1.
DR PRINTS; PR00481; LAMNOPPTDASE.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00631; CYTOSOL_AP; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000256|ARBA:ARBA00022438};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000002770}.
FT DOMAIN 302..309
FT /note="Cytosol aminopeptidase"
FT /evidence="ECO:0000259|PROSITE:PS00631"
SQ SEQUENCE 454 AA; 49605 MW; D3E875BC4868EF57 CRC64;
MYAELFYDTR SDRAIPLYLI SLTQWEEGID FLTPAERNSL AVKEFTGKVG DYCLISNADG
LVDKVYIGTG NGNQELALAN AALQLPASYY AVQGAMTQEA ALFWALAQYR FDRYKKNEVS
PRILAVKSEE LANLLALADA HFLVRDLVNK PTDDLGPTEM AAVVEELATT HGAEFKQWVG
DELLSANFPA IHAVGRAAIS APRLLSLTWG DALHPKVTLV GKGVCFDTGG LDIKSAYGMR
LMKKDMGGAA HVIGLAQWIM TRKLPVRLQM LVPAVENAIG PNAFRPGDVL TMRNGLTVEV
HNTDAEGRLV LADALVKACE EQPDLLIDFA TLTGAARVSV GTEVSALFTN NDQLATEVLD
ASCKAVDPMW RLPLFTPYED YLKSNMADMA NTSDHPYAGA IIASLFLQRF ITKSTVWMHL
DIMAWSERSK PGKPEGGEAM GLRAIAEYLL RVYG
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