ID G9F9M0_SPAAU Unreviewed; 468 AA.
AC G9F9M0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=SRY sex determining region Y-8 {ECO:0000313|EMBL:AEV53629.1};
GN Name=Sox8 {ECO:0000313|EMBL:AEV53629.1};
OS Sparus aurata (Gilthead sea bream).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Spariformes; Sparidae; Sparus.
OX NCBI_TaxID=8175 {ECO:0000313|EMBL:AEV53629.1};
RN [1] {ECO:0000313|EMBL:AEV53629.1}
RP NUCLEOTIDE SEQUENCE.
RA Garcia De La Serrana Castillo D., Codina M., Sanchez-Gurmaches J.,
RA Shao-Jun D., Capilla E., Navarro I., Joaquim G.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AEV53629.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=24157945; DOI=10.1016/j.cbpa.2013.10.020;
RA Garcia de la serrana D., Codina M., Capilla E., Jimenez-Amilburu V.,
RA Navarro I., Du S.J., Johnston I.A., Gutierrez J.;
RT "Characterisation and expression of myogenesis regulatory factors during in
RT vitro myoblast development and in vivo fasting in the gilthead sea bream
RT (Sparus aurata).";
RL Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 167:90-99(2014).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JN034419; AEV53629.1; -; mRNA.
DR AlphaFoldDB; G9F9M0; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22031; HMG-box_SoxE; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR022151; Sox_N.
DR PANTHER; PTHR45803; SOX100B; 1.
DR PANTHER; PTHR45803:SF2; TRANSCRIPTION FACTOR SOX-8; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF12444; Sox_N; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 2: Evidence at transcript level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}.
FT DOMAIN 100..168
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 100..168
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 152..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..180
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 51688 MW; A67EC901384BB91C CRC64;
MLKSTEEHDK CVGDQPCSPS GTNSSMSQDE SDSDAPSSPT GSDGHGSLLT GLGKKLDSED
DDRFPACIRD AVSQVLKGYD WSLVPMPVRG NGSLKNKPHV KRPMNAFMVW AQAARRKLAD
QYPHLHNAEL SKTLGKLWRL LSENEKRPFV EEAERLRVQH KKDHPDYKYQ PRRRKNVKPG
QSDSDSGAEL AHHMYKAEPG MGGLAGISDG HHHPEHAGQP HGPPTPPTTP KTDLHHGVTQ
DLKHEGRRLV DGSGQNIDFS NVDISELSTD VISNMETFRR ARVRPVPPAQ RPRLGLLRPA
LRPQPWAASG ACRILRFLLR PRGCQRAAWS RKGNMSSTSP SAGEVGQHRL HIKTEQLSPS
HYSEHSHRSP SHSDYSSYSS QACVTSASSA ASAAASFSSS QCDYTDIQSS NYYNPYSGYP
SSLYQYPYFH SSRRPYSSPI LNSLSMAPAH SPTASSWDQP VYTTLSRP
//
