ID G9II52_STRDR Unreviewed; 233 AA.
AC G9II52;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 12.
DE SubName: Full=SUREJ3 {ECO:0000313|EMBL:AEU11212.1};
DE Flags: Fragment;
GN Name=SUREJ3 {ECO:0000313|EMBL:AEU11212.1};
OS Strongylocentrotus droebachiensis (Green sea urchin).
OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea;
OC Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae;
OC Strongylocentrotus.
OX NCBI_TaxID=7671 {ECO:0000313|EMBL:AEU11212.1};
RN [1] {ECO:0000313|EMBL:AEU11212.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=22060977; DOI=10.1111/j.1365-294X.2011.05336.x;
RA Pujolar J.M., Pogson G.H.;
RT "Positive Darwinian selection in gamete recognition proteins of
RT Strongylocentrotus sea urchins.";
RL Mol. Ecol. 20:4968-4982(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the polycystin family.
CC {ECO:0000256|ARBA:ARBA00007200}.
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DR EMBL; JN669385; AEU11212.1; -; Genomic_DNA.
DR AlphaFoldDB; G9II52; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR013122; PKD1_2_channel.
DR InterPro; IPR046791; Polycystin_dom.
DR PANTHER; PTHR10877:SF195; POLYCYSTIC KIDNEY DISEASE 1 LIKE 2A-RELATED; 1.
DR PANTHER; PTHR10877; POLYCYSTIN FAMILY MEMBER; 1.
DR Pfam; PF08016; PKD_channel; 1.
DR Pfam; PF20519; Polycystin_dom; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 163..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..155
FT /note="Polycystin"
FT /evidence="ECO:0000259|Pfam:PF20519"
FT DOMAIN 156..232
FT /note="Polycystin cation channel PKD1/PKD2"
FT /evidence="ECO:0000259|Pfam:PF08016"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AEU11212.1"
FT NON_TER 233
FT /evidence="ECO:0000313|EMBL:AEU11212.1"
SQ SEQUENCE 233 AA; 27074 MW; 2F320682528BD3AA CRC64;
SCETHPLFVD LINDCRALFT PESEDRELYN ASWSQPIVNM SALLNSSQTV EEWSLSNYSP
WHFYPDKAVG MWGHATSLPS SGYIWVLGSM YEEAKDSLAE MVDARWLDAR TRALFVEWTS
YNANTNLFCV VTFLMETPAS GGLLKLPEVQ AVRLHRYAAN YKLFVILCEI LFVVALFFVM
YREYVRYKPI GIRKYLSDKW HLLEIAIIVN CIVSAGLYIY RYVITRQLFK QMR
//
