ID G9KML6_MUSPF Unreviewed; 618 AA.
AC G9KML6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Sex comb on midleg-like protein 1 {ECO:0000313|EMBL:AES06145.1};
DE Flags: Fragment;
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|EMBL:AES06145.1};
RN [1] {ECO:0000313|EMBL:AES06145.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Lungs {ECO:0000313|EMBL:AES06145.1};
RX PubMed=23236062; DOI=10.1128/JVI.02476-12;
RA Leon A.J., Banner D., Xu L., Ran L., Peng Z., Yi K., Chen C., Xu F.,
RA Huang J., Zhao Z., Lin Z., Huang S.H., Fang Y., Kelvin A.A., Ross T.M.,
RA Farooqui A., Kelvin D.J.;
RT "Sequencing, annotation, and characterization of the influenza ferret
RT infectome.";
RL J. Virol. 87:1957-1966(2013).
CC -!- SIMILARITY: Belongs to the SCM family. {ECO:0000256|ARBA:ARBA00008469}.
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DR EMBL; JP017547; AES06145.1; -; mRNA.
DR AlphaFoldDB; G9KML6; -.
DR HOGENOM; CLU_015000_1_1_1; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20105; MBT_SCMH1_rpt1; 1.
DR CDD; cd20108; MBT_SCMH1_rpt2; 1.
DR CDD; cd09578; SAM_Scm; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.90.1150.190; SLED domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR047279; MBT_SCMH1_rpt1.
DR InterPro; IPR047280; MBT_SCMH1_rpt2.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR047531; SAM_Scm-like.
DR InterPro; IPR033763; SCML2_RBR.
DR InterPro; IPR021987; SLED.
DR InterPro; IPR038348; SLED_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF68; POLYCOMB PROTEIN SCMH1; 1.
DR Pfam; PF02820; MBT; 2.
DR Pfam; PF17208; RBR; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF12140; SLED; 1.
DR SMART; SM00561; MBT; 2.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS51079; MBT; 2.
PE 2: Evidence at transcript level;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT REPEAT 4..102
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 110..211
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT DOMAIN 549..617
FT /note="SAM"
FT /evidence="ECO:0000259|SMART:SM00454"
FT REGION 209..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AES06145.1"
FT NON_TER 618
FT /evidence="ECO:0000313|EMBL:AES06145.1"
SQ SEQUENCE 618 AA; 68629 MW; 10D52510C8C59D9E CRC64;
LGHFTWDKYL KETCSVPAPV HCFKQSYTPP SNEFKISMKL EAQDPRNTTS TCIATVVGLT
GARLRLRLDG SDNKNDFWRL VDSAEIQPIG NCEKNGGMLQ PPLGFRLNAS SWPMFLLKTL
NGAEMAPIRI FHKEPPSPSH NFFKMGMKLE AVDRKNPHFI CPATIGEVRG SEVLVTFDGW
RGAFDYWCRF DSRDIFPVGW CSLTGDNLQP PGTKVVIPKN PYPASDVNTE KPSLHSSTKT
VLDHQPGQRG RKPGKKRGRT PKPLIPHPIS TPSKSAEPLK FPKKRGPKPG SKRKPRTLLN
PPPTSPTTST PEPDTSTVPQ DAATIPSSAM QAPTVCIYLN KNGSPGPHLD KKKVQLLPDH
FGPARASVVL QQAVQACIDC AYHQKTVFSF LKQGHGGEVI SAVFDREQHT LNLPAVNSIT
YVLRFLEKLC HNLRSDNLFG NQPFTQTHLP LTTTEYGHSR DRYLPGESFV LGKSLTRSLE
PHSDSMDSTL NPTNLVSSSQ NLRTHGYRPL VPSCGLPLGT ASAVRRLCSR GSDRYLESRD
ASRLTGRDPS SWTVEDVMQF VREADPQLGP HADLFRKHEI DGKALLLLRS DMMMKYMGLK
LGPALKLSFH IDRLKQGK
//
